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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bromodomain-containing protein 4 (124/124 = 100%)† (Homo sapiens (Human)) | BDBM50432486 (CHEMBL2349349) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of FITC-labeled (+)-JQ1 from bromodomain BRD4(1) (unknown origin) expressed in Escherichia coli BL21(DE3) after 4 hrs by fluorescence an... | J Med Chem 56: 3833-51 (2013) Article DOI: 10.1021/jm301793a BindingDB Entry DOI: 10.7270/Q2P55PVX | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Bromodomain-containing protein 4 (124/124 = 100%)† (Homo sapiens (Human)) | BDBM50432486 (CHEMBL2349349) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Institute of Materia Medica Curated by ChEMBL | Assay Description Inhibition of BRD4(1) (unknown origin) incubated for 4 hrs by (+)-JQ1 fluorescent ligand based fluorescence anisotrophy | J Med Chem 58: 1281-97 (2015) Article DOI: 10.1021/jm501504k BindingDB Entry DOI: 10.7270/Q2P270TX | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
