Affinity Data by PDB ID

PDB code 4Q8Y

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (260/260 = 100%)^† (Homo sapiens (Human))	BDBM50057415 (CHEMBL3326438) Show SMILES On1ccc2ccccc2c1=S Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	2.30E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase using p-nitrophenylacetate as substrate preincubated for 10 mins before substrate addition by spectrophotometr...				J Med Chem 57: 7126-35 (2014) Article DOI: 10.1021/jm500984b BindingDB Entry DOI: 10.7270/Q20V8FD1
University of California Curated by ChEMBL					More data for this Ligand-Target Pair

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output