Affinity Data by PDB ID

PDB code 5EWH

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peregrin (115/116 > 99%)^† (Homo sapiens (Human))	BDBM50240538 (CHEMBL57481 \| Isoquinolin-5-ol) Show SMILES Oc1cccc2cnccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
University of Z£rich Curated by ChEMBL					Assay Description Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assay				J Med Chem 59: 5555-61 (2016) Article DOI: 10.1021/acs.jmedchem.6b00215 BindingDB Entry DOI: 10.7270/Q22Z17GF
University of Z£rich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output