Affinity Data by PDB ID

PDB code 6KDJ

Found 2 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (534/555 = 96%)^† (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate \| CHEMBL1230 \| LAMIVUDINE \| Lamiv...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biota, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against HIV-1 reverse transcriptase				J Med Chem 48: 2695-700 (2005) Article DOI: 10.1021/jm040101y BindingDB Entry DOI: 10.7270/Q2G73FG5
Biota, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (534/555 = 96%)^† (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate \| CHEMBL1230 \| LAMIVUDINE \| Lamiv...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Equilibrium binding constant at the active site of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 437-40 (2003) BindingDB Entry DOI: 10.7270/Q2RX9BGK
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output