Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075067
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-15(2)12-19(27)25(32)29-39(33,34)35-13-21-22(30)23(31)24(37-21)26-28-20(14-38-26)16-8-10-18(11-9-16)36-17-6-4-3-5-7-17/h3-11,14-15,19,21-24,30-31H,12-13,27H2,1-2H3,(H,29,32)/t19-,21+,22+,23+,24+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075069
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-13(2)10-16(23)21(28)25-34(29,30)31-11-17-18(26)19(27)20(32-17)22-24-15(12-33-22)9-8-14-6-4-3-5-7-14/h3-7,12-13,16-20,26-27H,8-11,23H2,1-2H3,(H,25,28)/t16-,17+,18+,19+,20+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | <2 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075055
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-17(2)14-22(29)27(34)31-41(35,36)37-15-23-24(32)25(33)26(39-23)28-30-19(16-40-28)11-8-18-9-12-21(13-10-18)38-20-6-4-3-5-7-20/h3-7,9-10,12-13,16-17,22-26,32-33H,8,11,14-15,29H2,1-2H3,(H,31,34)/t22-,23+,24+,25+,26+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075058
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cccc(OC)c1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-6-5-7-13(8-12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075061
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc2cc(OC)ccc2c1 Show InChI InChI=1S/C25H31N3O8S2/c1-4-13(2)20(26)24(31)28-38(32,33)35-11-19-21(29)22(30)23(36-19)25-27-18(12-37-25)16-6-5-15-10-17(34-3)8-7-14(15)9-16/h5-10,12-13,19-23,29-30H,4,11,26H2,1-3H3,(H,28,31)/t13?,19-,20+,21-,22-,23-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075056
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-3-13(2)17(23)21(28)25-34(29,30)31-11-16-18(26)19(27)20(32-16)22-24-15(12-33-22)10-9-14-7-5-4-6-8-14/h4-8,12-13,16-20,26-27H,3,9-11,23H2,1-2H3,(H,25,28)/t13?,16-,17+,18-,19-,20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075059
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1OC Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-13(10-33-21)12-7-5-6-8-14(12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075058
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cccc(OC)c1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-6-5-7-13(8-12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075056
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-3-13(2)17(23)21(28)25-34(29,30)31-11-16-18(26)19(27)20(32-16)22-24-15(12-33-22)10-9-14-7-5-4-6-8-14/h4-8,12-13,16-20,26-27H,3,9-11,23H2,1-2H3,(H,25,28)/t13?,16-,17+,18-,19-,20-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075056
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-3-13(2)17(23)21(28)25-34(29,30)31-11-16-18(26)19(27)20(32-16)22-24-15(12-33-22)10-9-14-7-5-4-6-8-14/h4-8,12-13,16-20,26-27H,3,9-11,23H2,1-2H3,(H,25,28)/t13?,16-,17+,18-,19-,20-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075070
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-3-15(2)21(27)25(32)29-39(33,34)35-13-20-22(30)23(31)24(37-20)26-28-19(14-38-26)16-9-11-18(12-10-16)36-17-7-5-4-6-8-17/h4-12,14-15,20-24,30-31H,3,13,27H2,1-2H3,(H,29,32)/t15?,20-,21+,22-,23-,24-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075058
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cccc(OC)c1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-6-5-7-13(8-12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075067
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-15(2)12-19(27)25(32)29-39(33,34)35-13-21-22(30)23(31)24(37-21)26-28-20(14-38-26)16-8-10-18(11-9-16)36-17-6-4-3-5-7-17/h3-11,14-15,19,21-24,30-31H,12-13,27H2,1-2H3,(H,29,32)/t19-,21+,22+,23+,24+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >54 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075069
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-13(2)10-16(23)21(28)25-34(29,30)31-11-17-18(26)19(27)20(32-17)22-24-15(12-33-22)9-8-14-6-4-3-5-7-14/h3-7,12-13,16-20,26-27H,8-11,23H2,1-2H3,(H,25,28)/t16-,17+,18+,19+,20+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075063
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-5-7-13(30-3)8-6-12/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075055
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-17(2)14-22(29)27(34)31-41(35,36)37-15-23-24(32)25(33)26(39-23)28-30-19(16-40-28)11-8-18-9-12-21(13-10-18)38-20-6-4-3-5-7-20/h3-7,9-10,12-13,16-17,22-26,32-33H,8,11,14-15,29H2,1-2H3,(H,31,34)/t22-,23+,24+,25+,26+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075063
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-5-7-13(30-3)8-6-12/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075065
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-3-17(2)23(29)27(34)31-41(35,36)37-15-22-24(32)25(33)26(39-22)28-30-19(16-40-28)12-9-18-10-13-21(14-11-18)38-20-7-5-4-6-8-20/h4-8,10-11,13-14,16-17,22-26,32-33H,3,9,12,15,29H2,1-2H3,(H,31,34)/t17?,22-,23+,24-,25-,26-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075065
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-3-17(2)23(29)27(34)31-41(35,36)37-15-22-24(32)25(33)26(39-22)28-30-19(16-40-28)12-9-18-10-13-21(14-11-18)38-20-7-5-4-6-8-20/h4-8,10-11,13-14,16-17,22-26,32-33H,3,9,12,15,29H2,1-2H3,(H,31,34)/t17?,22-,23+,24-,25-,26-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075062
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cc(co1)C#N Show InChI InChI=1S/C19H24N4O8S2/c1-3-9(2)14(21)18(26)23-33(27,28)30-7-13-15(24)16(25)17(31-13)19-22-11(8-32-19)12-4-10(5-20)6-29-12/h4,6,8-9,13-17,24-25H,3,7,21H2,1-2H3,(H,23,26)/t9?,13-,14+,15-,16-,17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075061
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc2cc(OC)ccc2c1 Show InChI InChI=1S/C25H31N3O8S2/c1-4-13(2)20(26)24(31)28-38(32,33)35-11-19-21(29)22(30)23(36-19)25-27-18(12-37-25)16-6-5-15-10-17(34-3)8-7-14(15)9-16/h5-10,12-13,19-23,29-30H,4,11,26H2,1-3H3,(H,28,31)/t13?,19-,20+,21-,22-,23-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075063
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(OC)cc1 Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-14(10-33-21)12-5-7-13(30-3)8-6-12/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075062
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cc(co1)C#N Show InChI InChI=1S/C19H24N4O8S2/c1-3-9(2)14(21)18(26)23-33(27,28)30-7-13-15(24)16(25)17(31-13)19-22-11(8-32-19)12-4-10(5-20)6-29-12/h4,6,8-9,13-17,24-25H,3,7,21H2,1-2H3,(H,23,26)/t9?,13-,14+,15-,16-,17-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075062
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1cc(co1)C#N Show InChI InChI=1S/C19H24N4O8S2/c1-3-9(2)14(21)18(26)23-33(27,28)30-7-13-15(24)16(25)17(31-13)19-22-11(8-32-19)12-4-10(5-20)6-29-12/h4,6,8-9,13-17,24-25H,3,7,21H2,1-2H3,(H,23,26)/t9?,13-,14+,15-,16-,17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075070
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-3-15(2)21(27)25(32)29-39(33,34)35-13-20-22(30)23(31)24(37-20)26-28-19(14-38-26)16-9-11-18(12-10-16)36-17-7-5-4-6-8-17/h4-12,14-15,20-24,30-31H,3,13,27H2,1-2H3,(H,29,32)/t15?,20-,21+,22-,23-,24-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075059
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1OC Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-13(10-33-21)12-7-5-6-8-14(12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075059
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1OC Show InChI InChI=1S/C21H29N3O8S2/c1-4-11(2)16(22)20(27)24-34(28,29)31-9-15-17(25)18(26)19(32-15)21-23-13(10-33-21)12-7-5-6-8-14(12)30-3/h5-8,10-11,15-19,25-26H,4,9,22H2,1-3H3,(H,24,27)/t11?,15-,16+,17-,18-,19-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075070
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-3-15(2)21(27)25(32)29-39(33,34)35-13-20-22(30)23(31)24(37-20)26-28-19(14-38-26)16-9-11-18(12-10-16)36-17-7-5-4-6-8-17/h4-12,14-15,20-24,30-31H,3,13,27H2,1-2H3,(H,29,32)/t15?,20-,21+,22-,23-,24-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075061
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc2cc(OC)ccc2c1 Show InChI InChI=1S/C25H31N3O8S2/c1-4-13(2)20(26)24(31)28-38(32,33)35-11-19-21(29)22(30)23(36-19)25-27-18(12-37-25)16-6-5-15-10-17(34-3)8-7-14(15)9-16/h5-10,12-13,19-23,29-30H,4,11,26H2,1-3H3,(H,28,31)/t13?,19-,20+,21-,22-,23-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075067
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H31N3O8S2/c1-15(2)12-19(27)25(32)29-39(33,34)35-13-21-22(30)23(31)24(37-21)26-28-20(14-38-26)16-8-10-18(11-9-16)36-17-6-4-3-5-7-17/h3-11,14-15,19,21-24,30-31H,12-13,27H2,1-2H3,(H,29,32)/t19-,21+,22+,23+,24+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075069
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccccc2)cs1 Show InChI InChI=1S/C22H31N3O7S2/c1-13(2)10-16(23)21(28)25-34(29,30)31-11-17-18(26)19(27)20(32-17)22-24-15(12-33-22)9-8-14-6-4-3-5-7-14/h3-7,12-13,16-20,26-27H,8-11,23H2,1-2H3,(H,25,28)/t16-,17+,18+,19+,20+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075065
(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CCC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-3-17(2)23(29)27(34)31-41(35,36)37-15-22-24(32)25(33)26(39-22)28-30-19(16-40-28)12-9-18-10-13-21(14-11-18)38-20-7-5-4-6-8-20/h4-8,10-11,13-14,16-17,22-26,32-33H,3,9,12,15,29H2,1-2H3,(H,31,34)/t17?,22-,23+,24-,25-,26-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075055
(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)Show SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1 Show InChI InChI=1S/C28H35N3O8S2/c1-17(2)14-22(29)27(34)31-41(35,36)37-15-23-24(32)25(33)26(39-23)28-30-19(16-40-28)11-8-18-9-12-21(13-10-18)38-20-6-4-3-5-7-20/h3-7,9-10,12-13,16-17,22-26,32-33H,8,11,14-15,29H2,1-2H3,(H,31,34)/t22-,23+,24+,25+,26+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Staphylococcus aureus) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075064
(((S)-2-Amino-3-methyl-butyryl)-sulfamic acid (2R,3...)Show SMILES CC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C19H25N3O7S2/c1-10(2)14(20)18(25)22-31(26,27)28-8-13-15(23)16(24)17(29-13)19-21-12(9-30-19)11-6-4-3-5-7-11/h3-7,9-10,13-17,23-24H,8,20H2,1-2H3,(H,22,25)/t13-,14+,15-,16-,17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075064
(((S)-2-Amino-3-methyl-butyryl)-sulfamic acid (2R,3...)Show SMILES CC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C19H25N3O7S2/c1-10(2)14(20)18(25)22-31(26,27)28-8-13-15(23)16(24)17(29-13)19-21-12(9-30-19)11-6-4-3-5-7-11/h3-7,9-10,13-17,23-24H,8,20H2,1-2H3,(H,22,25)/t13-,14+,15-,16-,17-/m1/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of human isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Alanine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075057
(CHEMBL126919 | [(S)-2-Amino-3-(3H-imidazol-4-yl)-p...)Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H23N5O7S2/c21-13(6-12-7-22-10-23-12)19(28)25-34(29,30)31-8-15-16(26)17(27)18(32-15)20-24-14(9-33-20)11-4-2-1-3-5-11/h1-5,7,9-10,13,15-18,26-27H,6,8,21H2,(H,22,23)(H,25,28)/t13-,15+,16+,17+,18+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Alanine-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075057
(CHEMBL126919 | [(S)-2-Amino-3-(3H-imidazol-4-yl)-p...)Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H23N5O7S2/c21-13(6-12-7-22-10-23-12)19(28)25-34(29,30)31-8-15-16(26)17(27)18(32-15)20-24-14(9-33-20)11-4-2-1-3-5-11/h1-5,7,9-10,13,15-18,26-27H,6,8,21H2,(H,22,23)(H,25,28)/t13-,15+,16+,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Alanine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075066
(((S)-2-Amino-propionyl)-sulfamic acid (2R,3S,4R,5R...)Show SMILES C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C17H21N3O7S2/c1-9(18)16(23)20-29(24,25)26-7-12-13(21)14(22)15(27-12)17-19-11(8-28-17)10-5-3-2-4-6-10/h2-6,8-9,12-15,21-22H,7,18H2,1H3,(H,20,23)/t9-,12+,13+,14+,15+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Alanine-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075060
(((S)-2-Amino-3-phenyl-propionyl)-sulfamic acid (2R...)Show SMILES N[C@@H](Cc1ccccc1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C23H25N3O7S2/c24-16(11-14-7-3-1-4-8-14)22(29)26-35(30,31)32-12-18-19(27)20(28)21(33-18)23-25-17(13-34-23)15-9-5-2-6-10-15/h1-10,13,16,18-21,27-28H,11-12,24H2,(H,26,29)/t16-,18+,19+,20+,21+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Alanine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Alanine-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075066
(((S)-2-Amino-propionyl)-sulfamic acid (2R,3S,4R,5R...)Show SMILES C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C17H21N3O7S2/c1-9(18)16(23)20-29(24,25)26-7-12-13(21)14(22)15(27-12)17-19-11(8-28-17)10-5-3-2-4-6-10/h2-6,8-9,12-15,21-22H,7,18H2,1H3,(H,20,23)/t9-,12+,13+,14+,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Alanine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075060
(((S)-2-Amino-3-phenyl-propionyl)-sulfamic acid (2R...)Show SMILES N[C@@H](Cc1ccccc1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C23H25N3O7S2/c24-16(11-14-7-3-1-4-8-14)22(29)26-35(30,31)32-12-18-19(27)20(28)21(33-18)23-25-17(13-34-23)15-9-5-2-6-10-15/h1-10,13,16,18-21,27-28H,11-12,24H2,(H,26,29)/t16-,18+,19+,20+,21+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Alanine-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075057
(CHEMBL126919 | [(S)-2-Amino-3-(3H-imidazol-4-yl)-p...)Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H23N5O7S2/c21-13(6-12-7-22-10-23-12)19(28)25-34(29,30)31-8-15-16(26)17(27)18(32-15)20-24-14(9-33-20)11-4-2-1-3-5-11/h1-5,7,9-10,13,15-18,26-27H,6,8,21H2,(H,22,23)(H,25,28)/t13-,15+,16+,17+,18+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075066
(((S)-2-Amino-propionyl)-sulfamic acid (2R,3S,4R,5R...)Show SMILES C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C17H21N3O7S2/c1-9(18)16(23)20-29(24,25)26-7-12-13(21)14(22)15(27-12)17-19-11(8-28-17)10-5-3-2-4-6-10/h2-6,8-9,12-15,21-22H,7,18H2,1H3,(H,20,23)/t9-,12+,13+,14+,15+/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Alanine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075064
(((S)-2-Amino-3-methyl-butyryl)-sulfamic acid (2R,3...)Show SMILES CC(C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C19H25N3O7S2/c1-10(2)14(20)18(25)22-31(26,27)28-8-13-15(23)16(24)17(29-13)19-21-12(9-30-19)11-6-4-3-5-7-11/h3-7,9-10,13-17,23-24H,8,20H2,1-2H3,(H,22,25)/t13-,14+,15-,16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Alanine-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075060
(((S)-2-Amino-3-phenyl-propionyl)-sulfamic acid (2R...)Show SMILES N[C@@H](Cc1ccccc1)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C23H25N3O7S2/c24-16(11-14-7-3-1-4-8-14)22(29)26-35(30,31)32-12-18-19(27)20(28)21(33-18)23-25-17(13-34-23)15-9-5-2-6-10-15/h1-10,13,16,18-21,27-28H,11-12,24H2,(H,26,29)/t16-,18+,19+,20+,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Compound tested for the inhibition of E. coli Leucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Leucine--tRNA ligase, cytoplasmic
(Homo sapiens (Human)) | BDBM50075068
(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O7S2/c1-3-11(2)15(21)19(26)23-32(27,28)29-9-14-16(24)17(25)18(30-14)20-22-13(10-31-20)12-7-5-4-6-8-12/h4-8,10-11,14-18,24-25H,3,9,21H2,1-2H3,(H,23,26)/t11-,14+,15-,16+,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cubist Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of E. coli isoleucyl-tRNA synthetase |
Bioorg Med Chem Lett 9: 375-80 (1999)
BindingDB Entry DOI: 10.7270/Q2M32TX1 |
More data for this
Ligand-Target Pair | |
Search and Browse
