Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Growth factor receptor-bound protein 2 (Homo sapiens (Human)) | BDBM50078348 (CHEMBL77689 | [(S)-1-[1-((S)-1,2-Dicarbamoyl-ethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain | J Med Chem 42: 2358-63 (1999) Article DOI: 10.1021/jm991013u BindingDB Entry DOI: 10.7270/Q2S181PH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Growth factor receptor-bound protein 2 (Homo sapiens (Human)) | BDBM50078347 (CHEMBL307890 | [(S)-1-[1-((1R,6S)-6-Carbamoyl-cycl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain | J Med Chem 42: 2358-63 (1999) Article DOI: 10.1021/jm991013u BindingDB Entry DOI: 10.7270/Q2S181PH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Growth factor receptor-bound protein 2 (Homo sapiens (Human)) | BDBM50078346 (CHEMBL310056 | [(S)-1-[1-((1S,6R)-6-Carbamoyl-cycl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain | J Med Chem 42: 2358-63 (1999) Article DOI: 10.1021/jm991013u BindingDB Entry DOI: 10.7270/Q2S181PH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |