Affinity Data by PubMed id=10522707

PubMed code 10522707

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Genome polyprotein (Human rhinovirus B)	BDBM50081842 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by HPLC assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081846 (2-(1-Acetyl-2-oxo-propyl)-3-chloro-[1,4]naphthoqui...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by HPLC assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081842 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081846 (2-(1-Acetyl-2-oxo-propyl)-3-chloro-[1,4]naphthoqui...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081843 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081845 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM24774 (2,3-dichloro-1,4-dihydronaphthalene-1,4-dione \| 2,...) Show SMILES ClC1=C(Cl)C(=O)c2ccccc2C1=O \|c:1\| Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081843 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by HPLC assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM24774 (2,3-dichloro-1,4-dihydronaphthalene-1,4-dione \| 2,...) Show SMILES ClC1=C(Cl)C(=O)c2ccccc2C1=O \|c:1\| Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by HPLC assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081845 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by HPLC assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081847 (2-Chloro-3-(3-cyclohexyl-propyl)-[1,4]naphthoquino...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50081842 (2-(3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitoryactivity against human Elastase at 100 microM concentration				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081850 (2-Chloro-3-cycloheptyl-[1,4]naphthoquinone \| CHEMB...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081848 (2-Cyclohexyl-3-cyclohexyloxy-[1,4]naphthoquinone \|...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081844 ((3-Chloro-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-a...) Show SMILES COC(=O)CC1=C(Cl)C(=O)c2ccccc2C1=O \|c:5\| Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50081849 (2-Chloro-3-(4,4-dimethyl-2,6-dioxo-cyclohexyl)-[1,...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibitory activity against HCMV protease by SPA assay				Bioorg Med Chem Lett 9: 2863-6 (1999) BindingDB Entry DOI: 10.7270/Q298867T
GlaxoWellcome Medicines Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%