Affinity Data by PubMed id=10571154

PubMed code 10571154

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM7882 (1H-imidazole \| CHEMBL540 \| Imidazole (Im) \| US9138...) Show SMILES c1c[nH]cn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50082309 (CHEMBL101317 \| N-(1H-Imidazol-2-ylmethyl)-guanidin...) Show SMILES NC(=N)NCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50082307 ((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...) Show SMILES N[C@H](CCCNC(=N)NCc1ncc[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.47E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50082310 ((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...) Show SMILES N[C@H](CCCNC(=N)NCCc1ncc[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50078824 (2-Phenyl-1H-imidazole \| CHEMBL14189 \| US9138393, 2...) Show SMILES c1c[nH]c(n1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50082308 ((R)-2-Amino-5-{N'-[2-(3H-imidazol-4-yl)-ethyl]-gua...) Show SMILES N[C@H](CCCNC(=N)NCCc1cnc[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.09E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of bovine endothelial nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 ...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50082310 ((R)-2-Amino-5-{N'-[2-(1H-imidazol-2-yl)-ethyl]-gua...) Show SMILES N[C@H](CCCNC(=N)NCCc1ncc[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.49E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-a...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50082307 ((R)-2-Amino-5-[N'-(1H-imidazol-2-ylmethyl)-guanidi...) Show SMILES N[C@H](CCCNC(=N)NCc1ncc[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.59E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Winston-Salem Curated by ChEMBL					Assay Description Inhibition of rat neuronal nitric oxide synthase catalyzed [14C]-L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-a...				Bioorg Med Chem Lett 9: 2953-8 (1999) BindingDB Entry DOI: 10.7270/Q27943W9
Wake Forest University Winston-Salem Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%