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PubMed code 10714507

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thymidylate synthase


(Lactobacillus casei)
BDBM50085615
PNG
(CHEMBL3143067 | Phosphoric acid mono-{5-[5-(3-fluo...)
Show SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1cc(C#CCF)c(=O)[nH]c1=O |r|
Show InChI InChI=1S/C12H14FN2O8P/c13-3-1-2-7-5-15(12(18)14-11(7)17)10-4-8(16)9(23-10)6-22-24(19,20)21/h5,8-10,16H,3-4,6H2,(H,14,17,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
15n/an/an/an/an/an/an/an/a



State University of New York

Curated by ChEMBL


Assay Description
The compound was evaluated for the binding affinity against L. casei dTMP synthase using spectrophotometric assay


Bioorg Med Chem Lett 10: 391-4 (2000)


BindingDB Entry DOI: 10.7270/Q29P30VN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%