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PubMed code 10762050

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth factor receptor-bound protein 2


(Homo sapiens (Human))		BDBM50087242
PNG
(CHEMBL422705 | Pro-Ser-pTyr-Val-Asn-Val-Gln-Asn)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C40H62N11O17P/c1-18(2)31(38(61)45-23(11-12-28(41)53)34(57)48-26(40(63)64)16-30(43)55)51-36(59)25(15-29(42)54)47-39(62)32(19(3)4)50-35(58)24(14-20-7-9-21(10-8-20)68-69(65,66)67)46-37(60)27(17-52)49-33(56)22-6-5-13-44-22/h7-10,18-19,22-27,31-32,44,52H,5-6,11-17H2,1-4H3,(H2,41,53)(H2,42,54)(H2,43,55)(H,45,61)(H,46,60)(H,47,62)(H,48,57)(H,49,56)(H,50,58)(H,51,59)(H,63,64)(H2,65,66,67)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PubMed
n/an/an/a 18n/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence

Bioorg Med Chem Lett 10: 669-72 (2000)


BindingDB Entry DOI: 10.7270/Q2B857BR
More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Homo sapiens (Human))		BDBM50087243
PNG
(CHEMBL436789 | Pro-Ser-F2Pmp-Val-Asn-Val-Gln-Asn)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C41H62F2N11O16P/c1-18(2)31(38(64)48-23(11-12-28(44)56)34(60)51-26(40(66)67)16-30(46)58)54-36(62)25(15-29(45)57)50-39(65)32(19(3)4)53-35(61)24(14-20-7-9-21(10-8-20)41(42,43)71(68,69)70)49-37(63)27(17-55)52-33(59)22-6-5-13-47-22/h7-10,18-19,22-27,31-32,47,55H,5-6,11-17H2,1-4H3,(H2,44,56)(H2,45,57)(H2,46,58)(H,48,64)(H,49,63)(H,50,65)(H,51,60)(H,52,59)(H,53,61)(H,54,62)(H,66,67)(H2,68,69,70)/t22-,23-,24-,25-,26-,27-,31-,32-/m0/s1
PDB
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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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PC cid
PC sid
UniChem

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PubMed
n/an/an/a 200n/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence

Bioorg Med Chem Lett 10: 669-72 (2000)


BindingDB Entry DOI: 10.7270/Q2B857BR
More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Homo sapiens (Human))		BDBM50087244
PNG
(Ac-Pro-Phe-pTyr-Val-Asn-Val-Pro-NH2 | CHEMBL237124...)
Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(N)=O
Show InChI InChI=1S/C44H62N9O13P/c1-24(2)36(43(61)49-32(23-35(45)55)41(59)51-37(25(3)4)44(62)53-20-9-13-33(53)38(46)56)50-40(58)31(22-28-15-17-29(18-16-28)66-67(63,64)65)47-39(57)30(21-27-11-7-6-8-12-27)48-42(60)34-14-10-19-52(34)26(5)54/h6-8,11-12,15-18,24-25,30-34,36-37H,9-10,13-14,19-23H2,1-5H3,(H2,45,55)(H2,46,56)(H,47,57)(H,48,60)(H,49,61)(H,50,58)(H,51,59)(H2,63,64,65)/t30-,31-,32-,33-,34-,36-,37-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/a 30n/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence

Bioorg Med Chem Lett 10: 669-72 (2000)


BindingDB Entry DOI: 10.7270/Q2B857BR
More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Homo sapiens (Human))		BDBM50087245
PNG
(CHEMBL345170 | Pro-Ser-Pmp-Val-Asn-Val-Gln-Asn)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
Show InChI InChI=1S/C41H64N11O16P/c1-19(2)32(39(62)46-24(11-12-29(42)54)35(58)49-27(41(64)65)16-31(44)56)52-37(60)26(15-30(43)55)48-40(63)33(20(3)4)51-36(59)25(14-21-7-9-22(10-8-21)18-69(66,67)68)47-38(61)28(17-53)50-34(57)23-6-5-13-45-23/h7-10,19-20,23-28,32-33,45,53H,5-6,11-18H2,1-4H3,(H2,42,54)(H2,43,55)(H2,44,56)(H,46,62)(H,47,61)(H,48,63)(H,49,58)(H,50,57)(H,51,59)(H,52,60)(H,64,65)(H2,66,67,68)/t23-,24-,25-,26-,27-,28-,32-,33-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/a 260n/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescence

Bioorg Med Chem Lett 10: 669-72 (2000)


BindingDB Entry DOI: 10.7270/Q2B857BR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%