Affinity Data by PubMed id=10866390

PubMed code 10866390

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50004881 ((RS) PPG \| Amino-(4-phosphono-phenyl)-acetic acid ...) Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7b				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50004881 ((RS) PPG \| Amino-(4-phosphono-phenyl)-acetic acid ...) Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50004881 ((RS) PPG \| Amino-(4-phosphono-phenyl)-acetic acid ...) Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7b				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007547 (1-Amino-2-phosphonomethyl-cyclopropanecarboxylic a...) Show SMILES NC1(CC1CP(O)(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Effective concentration of the compound against Metabotropic glutamate receptor 4				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50004881 ((RS) PPG \| Amino-(4-phosphono-phenyl)-acetic acid ...) Show SMILES NC(C(O)=O)c1ccc(cc1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50004840 (Amino-(4-phosphonomethyl-phenyl)-acetic acid \| CHE...) Show SMILES NC(C(O)=O)c1ccc(CP(O)(O)=O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Dissociation constant of the compound against N-methyl-D-aspartate glutamate receptor using [3H]-CPP binding was determined				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50089105 (1-Amino-3-phosphonomethylene-cyclobutanecarboxylic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Effective concentration of the compound against rat Metabotropic glutamate receptor 4				Bioorg Med Chem Lett 10: 1241-4 (2000) BindingDB Entry DOI: 10.7270/Q26972SC
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%