Affinity Data by PubMed id=10966747

PubMed code 10966747

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50091312 (8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oc...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]mazindol binding to dopamine transporter of rat striatal membranes.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366564 (CHEMBL1790051 \| CHEMBL83729 \| WIN-35065-2) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity uptake of [3H]dopamine into nerve endings (synaptosomes) prepared from various regions of the rat brain.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50091312 (8-Methyl-2-propyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oc...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity uptake of [3H]dopamine into nerve endings (synaptosomes) prepared from various regions of the rat brain.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366564 (CHEMBL1790051 \| CHEMBL83729 \| WIN-35065-2) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]mazindol binding to dopamine transporter of rat striatal membranes.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]mazindol binding to dopamine transporter of rat striatal membranes.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of high affinity uptake of [3H]dopamine into nerve endings (synaptosomes) prepared from various regions of the rat brain.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50091310 (9-Methyl-3-p-tolyl-6-oxa-9-aza-tricyclo[5.2.1.0*4,...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]mazindol binding to dopamine transporter of rat striatal membranes.				J Med Chem 43: 3283-94 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q62
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%