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PubMed code 10999472

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50091959
PNG
(Phosphoric acid mono-[4-(3-carbamoyl-4-cyclohexylm...)
Show SMILES NC(=O)c1cc(CNC(=O)c2ccc(OP([O-])([O-])=O)cc2)ccc1OCC1CCCCC1
Show InChI InChI=1S/C22H27N2O7P/c23-21(25)19-12-16(6-11-20(19)30-14-15-4-2-1-3-5-15)13-24-22(26)17-7-9-18(10-8-17)31-32(27,28)29/h6-12,15H,1-5,13-14H2,(H2,23,25)(H,24,26)(H2,27,28,29)/p-2
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PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Binding affinity for Human pp60c-src SH2 domain

Bioorg Med Chem Lett 10: 2067-70 (2000)


BindingDB Entry DOI: 10.7270/Q29Z95FC
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50091961
PNG
(Phosphoric acid mono-[4-(4-cyclohexylmethoxy-3-met...)
Show SMILES CNC(=O)c1cc(CNC(=O)c2ccc(OP([O-])([O-])=O)cc2)ccc1OCC1CCCCC1
Show InChI InChI=1S/C23H29N2O7P/c1-24-23(27)20-13-17(7-12-21(20)31-15-16-5-3-2-4-6-16)14-25-22(26)18-8-10-19(11-9-18)32-33(28,29)30/h7-13,16H,2-6,14-15H2,1H3,(H,24,27)(H,25,26)(H2,28,29,30)/p-2
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PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Binding affinity for Human pp60c-src SH2 domain

Bioorg Med Chem Lett 10: 2067-70 (2000)


BindingDB Entry DOI: 10.7270/Q29Z95FC
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50091958
PNG
(Phosphoric acid mono-[4-(3-acetyl-4-cyclohexylmeth...)
Show SMILES CC(=O)c1cc(CNC(=O)c2ccc(OP([O-])([O-])=O)cc2)ccc1OCC1CCCCC1
Show InChI InChI=1S/C23H28NO7P/c1-16(25)21-13-18(7-12-22(21)30-15-17-5-3-2-4-6-17)14-24-23(26)19-8-10-20(11-9-19)31-32(27,28)29/h7-13,17H,2-6,14-15H2,1H3,(H,24,26)(H2,27,28,29)/p-2
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UniProtKB/SwissProt

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UniChem

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PubMed
n/an/a 6.90E+4n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Binding affinity for Human pp60c-src SH2 domain

Bioorg Med Chem Lett 10: 2067-70 (2000)


BindingDB Entry DOI: 10.7270/Q29Z95FC
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50091960
PNG
(Phosphoric acid mono-[4-(4-cyclohexylmethoxy-benzy...)
Show SMILES [O-]P([O-])(=O)Oc1ccc(cc1)C(=O)NCc1ccc(OCC2CCCCC2)cc1
Show InChI InChI=1S/C21H26NO6P/c23-21(18-8-12-20(13-9-18)28-29(24,25)26)22-14-16-6-10-19(11-7-16)27-15-17-4-2-1-3-5-17/h6-13,17H,1-5,14-15H2,(H,22,23)(H2,24,25,26)/p-2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Binding affinity for Human pp60c-src SH2 domain

Bioorg Med Chem Lett 10: 2067-70 (2000)


BindingDB Entry DOI: 10.7270/Q29Z95FC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%