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PubMed code 11133079

Compile data set for download or QSAR
Found 10 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50095116
PNG
((R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-...)
Show SMILES NCCCC1CCCN2C1C(=O)N(Cc1cccc3ccccc13)CCS[C@H](Cc1c[nH]c3ccccc13)C2=O
Show InChI InChI=1S/C33H38N4O2S/c34-16-6-11-24-12-7-17-37-31(24)33(39)36(22-25-10-5-9-23-8-1-2-13-27(23)25)18-19-40-30(32(37)38)20-26-21-35-29-15-4-3-14-28(26)29/h1-5,8-10,13-15,21,24,30-31,35H,6-7,11-12,16-20,22,34H2/t24?,30-,31?/m1/s1
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n/an/a 41n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 5 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50095116
PNG
((R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-...)
Show SMILES NCCCC1CCCN2C1C(=O)N(Cc1cccc3ccccc13)CCS[C@H](Cc1c[nH]c3ccccc13)C2=O
Show InChI InChI=1S/C33H38N4O2S/c34-16-6-11-24-12-7-17-37-31(24)33(39)36(22-25-10-5-9-23-8-1-2-13-27(23)25)18-19-40-30(32(37)38)20-26-21-35-29-15-4-3-14-28(26)29/h1-5,8-10,13-15,21,24,30-31,35H,6-7,11-12,16-20,22,34H2/t24?,30-,31?/m1/s1
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n/an/a 41n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 4 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))		BDBM50095115
PNG
((1R,9R)-5-(4-Amino-butyl)-2-(1H-indol-3-ylmethyl)-...)
Show SMILES NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O |r|
Show InChI InChI=1S/C30H34N4O2S/c31-15-6-5-14-27-30(36)34(20-22-10-7-9-21-8-1-2-11-24(21)22)16-17-37-28(29(35)33-27)18-23-19-32-26-13-4-3-12-25(23)26/h1-4,7-13,19,27-28,32H,5-6,14-18,20,31H2,(H,33,35)/t27-,28-/m1/s1
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n/an/a 87n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 5 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50095116
PNG
((R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-...)
Show SMILES NCCCC1CCCN2C1C(=O)N(Cc1cccc3ccccc13)CCS[C@H](Cc1c[nH]c3ccccc13)C2=O
Show InChI InChI=1S/C33H38N4O2S/c34-16-6-11-24-12-7-17-37-31(24)33(39)36(22-25-10-5-9-23-8-1-2-13-27(23)25)18-19-40-30(32(37)38)20-26-21-35-29-15-4-3-14-28(26)29/h1-5,8-10,13-15,21,24,30-31,35H,6-7,11-12,16-20,22,34H2/t24?,30-,31?/m1/s1
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n/an/a 275n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 2 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50095116
PNG
((R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-...)
Show SMILES NCCCC1CCCN2C1C(=O)N(Cc1cccc3ccccc13)CCS[C@H](Cc1c[nH]c3ccccc13)C2=O
Show InChI InChI=1S/C33H38N4O2S/c34-16-6-11-24-12-7-17-37-31(24)33(39)36(22-25-10-5-9-23-8-1-2-13-27(23)25)18-19-40-30(32(37)38)20-26-21-35-29-15-4-3-14-28(26)29/h1-5,8-10,13-15,21,24,30-31,35H,6-7,11-12,16-20,22,34H2/t24?,30-,31?/m1/s1
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n/an/a 407n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))		BDBM50095115
PNG
((1R,9R)-5-(4-Amino-butyl)-2-(1H-indol-3-ylmethyl)-...)
Show SMILES NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O |r|
Show InChI InChI=1S/C30H34N4O2S/c31-15-6-5-14-27-30(36)34(20-22-10-7-9-21-8-1-2-11-24(21)22)16-17-37-28(29(35)33-27)18-23-19-32-26-13-4-3-12-25(23)26/h1-4,7-13,19,27-28,32H,5-6,14-18,20,31H2,(H,33,35)/t27-,28-/m1/s1
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n/an/a 501n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 1 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))		BDBM50095115
PNG
((1R,9R)-5-(4-Amino-butyl)-2-(1H-indol-3-ylmethyl)-...)
Show SMILES NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O |r|
Show InChI InChI=1S/C30H34N4O2S/c31-15-6-5-14-27-30(36)34(20-22-10-7-9-21-8-1-2-11-24(21)22)16-17-37-28(29(35)33-27)18-23-19-32-26-13-4-3-12-25(23)26/h1-4,7-13,19,27-28,32H,5-6,14-18,20,31H2,(H,33,35)/t27-,28-/m1/s1
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n/an/a 1.05E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 4 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50095116
PNG
((R)-1-(3-Amino-propyl)-6-(1H-indol-3-ylmethyl)-10-...)
Show SMILES NCCCC1CCCN2C1C(=O)N(Cc1cccc3ccccc13)CCS[C@H](Cc1c[nH]c3ccccc13)C2=O
Show InChI InChI=1S/C33H38N4O2S/c34-16-6-11-24-12-7-17-37-31(24)33(39)36(22-25-10-5-9-23-8-1-2-13-27(23)25)18-19-40-30(32(37)38)20-26-21-35-29-15-4-3-14-28(26)29/h1-5,8-10,13-15,21,24,30-31,35H,6-7,11-12,16-20,22,34H2/t24?,30-,31?/m1/s1
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n/an/a 1.26E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 3 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))		BDBM50095115
PNG
((1R,9R)-5-(4-Amino-butyl)-2-(1H-indol-3-ylmethyl)-...)
Show SMILES NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O |r|
Show InChI InChI=1S/C30H34N4O2S/c31-15-6-5-14-27-30(36)34(20-22-10-7-9-21-8-1-2-11-24(21)22)16-17-37-28(29(35)33-27)18-23-19-32-26-13-4-3-12-25(23)26/h1-4,7-13,19,27-28,32H,5-6,14-18,20,31H2,(H,33,35)/t27-,28-/m1/s1
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n/an/a 1.59E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 2 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))		BDBM50095115
PNG
((1R,9R)-5-(4-Amino-butyl)-2-(1H-indol-3-ylmethyl)-...)
Show SMILES NCCCC[C@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)SCCN(Cc2cccc3ccccc23)C1=O |r|
Show InChI InChI=1S/C30H34N4O2S/c31-15-6-5-14-27-30(36)34(20-22-10-7-9-21-8-1-2-11-24(21)22)16-17-37-28(29(35)33-27)18-23-19-32-26-13-4-3-12-25(23)26/h1-4,7-13,19,27-28,32H,5-6,14-18,20,31H2,(H,33,35)/t27-,28-/m1/s1
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n/an/a 3.09E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory concentration required for somatostatin 3 receptor in radioligand binding assay ([125I]-Tyr11-SRIF)

Bioorg Med Chem Lett 10: 2731-3 (2000)


BindingDB Entry DOI: 10.7270/Q2QC02RM
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%