Found 44 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Collagenase 3
(Homo sapiens (Human)) | BDBM50096472
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C23H23N3O8S/c1-33-17-10-12-18(13-11-17)35(31,32)26(14-16-6-3-2-4-7-16)22-19(23(28)25-30)8-5-9-20(22)34-15-21(27)24-29/h2-13,29-30H,14-15H2,1H3,(H,24,27)(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096472
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C23H23N3O8S/c1-33-17-10-12-18(13-11-17)35(31,32)26(14-16-6-3-2-4-7-16)22-19(23(28)25-30)8-5-9-20(22)34-15-21(27)24-29/h2-13,29-30H,14-15H2,1H3,(H,24,27)(H,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096467
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC(C)(C)C(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C25H27N3O8S/c1-25(2,24(30)27-32)36-21-11-7-10-20(23(29)26-31)22(21)28(16-17-8-5-4-6-9-17)37(33,34)19-14-12-18(35-3)13-15-19/h4-15,31-32H,16H2,1-3H3,(H,26,29)(H,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096468
(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COC(=O)c1cccc(C(=O)NO)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H21N3O7S/c1-31-16-8-10-17(11-9-16)33(29,30)25(14-15-5-4-12-23-13-15)20-18(21(26)24-28)6-3-7-19(20)22(27)32-2/h3-13,28H,14H2,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096463
(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C21H21N3O5S/c1-15-5-3-7-19(21(25)23-26)20(15)24(14-16-6-4-12-22-13-16)30(27,28)18-10-8-17(29-2)9-11-18/h3-13,26H,14H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096467
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC(C)(C)C(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C25H27N3O8S/c1-25(2,24(30)27-32)36-21-11-7-10-20(23(29)26-31)22(21)28(16-17-8-5-4-6-9-17)37(33,34)19-14-12-18(35-3)13-15-19/h4-15,31-32H,16H2,1-3H3,(H,26,29)(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096468
(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COC(=O)c1cccc(C(=O)NO)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H21N3O7S/c1-31-16-8-10-17(11-9-16)33(29,30)25(14-15-5-4-12-23-13-15)20-18(21(26)24-28)6-3-7-19(20)22(27)32-2/h3-13,28H,14H2,1-2H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096463
(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C21H21N3O5S/c1-15-5-3-7-19(21(25)23-26)20(15)24(14-16-6-4-12-22-13-16)30(27,28)18-10-8-17(29-2)9-11-18/h3-13,26H,14H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096471
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C21H19N3O7S/c1-31-16-10-12-17(13-11-16)32(29,30)23(14-15-6-3-2-4-7-15)20-18(21(25)22-26)8-5-9-19(20)24(27)28/h2-13,26H,14H2,1H3,(H,22,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096469
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(22(25)23-26)21(16)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096474
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O6S/c1-29-17-11-13-18(14-12-17)31(27,28)24(15-16-7-4-3-5-8-16)21-19(22(25)23-26)9-6-10-20(21)30-2/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096472
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C23H23N3O8S/c1-33-17-10-12-18(13-11-17)35(31,32)26(14-16-6-3-2-4-7-16)22-19(23(28)25-30)8-5-9-20(22)34-15-21(27)24-29/h2-13,29-30H,14-15H2,1H3,(H,24,27)(H,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096466
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1C(F)(F)F)C(=O)NO Show InChI InChI=1S/C22H19F3N2O5S/c1-32-16-10-12-17(13-11-16)33(30,31)27(14-15-6-3-2-4-7-15)20-18(21(28)26-29)8-5-9-19(20)22(23,24)25/h2-13,29H,14H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096475
(2-(N-benzyl-4-methoxyphenylsulfonamido)-3-chloro-N...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(Cl)cccc1C(=O)NO Show InChI InChI=1S/C21H19ClN2O5S/c1-29-16-10-12-17(13-11-16)30(27,28)24(14-15-6-3-2-4-7-15)20-18(21(25)23-26)8-5-9-19(20)22/h2-13,26H,14H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50096468
(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COC(=O)c1cccc(C(=O)NO)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H21N3O7S/c1-31-16-8-10-17(11-9-16)33(29,30)25(14-15-5-4-12-23-13-15)20-18(21(26)24-28)6-3-7-19(20)22(27)32-2/h3-13,28H,14H2,1-2H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha converting enzyme (TACE) |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096471
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C21H19N3O7S/c1-31-16-10-12-17(13-11-16)32(29,30)23(14-15-6-3-2-4-7-15)20-18(21(25)22-26)8-5-9-19(20)24(27)28/h2-13,26H,14H2,1H3,(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096469
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(22(25)23-26)21(16)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096470
(2-(N-benzyl-4-methoxyphenylsulfonamido)-3-(dimethy...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H25N3O5S/c1-25(2)21-11-7-10-20(23(27)24-28)22(21)26(16-17-8-5-4-6-9-17)32(29,30)19-14-12-18(31-3)13-15-19/h4-15,28H,16H2,1-3H3,(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50096472
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C23H23N3O8S/c1-33-17-10-12-18(13-11-17)35(31,32)26(14-16-6-3-2-4-7-16)22-19(23(28)25-30)8-5-9-20(22)34-15-21(27)24-29/h2-13,29-30H,14-15H2,1H3,(H,24,27)(H,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibition of TNF-alpha converting enzyme (TACE) |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096469
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(22(25)23-26)21(16)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096466
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1C(F)(F)F)C(=O)NO Show InChI InChI=1S/C22H19F3N2O5S/c1-32-16-10-12-17(13-11-16)33(30,31)27(14-15-6-3-2-4-7-15)20-18(21(28)26-29)8-5-9-19(20)22(23,24)25/h2-13,29H,14H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096474
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O6S/c1-29-17-11-13-18(14-12-17)31(27,28)24(15-16-7-4-3-5-8-16)21-19(22(25)23-26)9-6-10-20(21)30-2/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096463
(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO Show InChI InChI=1S/C21H21N3O5S/c1-15-5-3-7-19(21(25)23-26)20(15)24(14-16-6-4-12-22-13-16)30(27,28)18-10-8-17(29-2)9-11-18/h3-13,26H,14H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096471
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C21H19N3O7S/c1-31-16-10-12-17(13-11-16)32(29,30)23(14-15-6-3-2-4-7-15)20-18(21(25)22-26)8-5-9-19(20)24(27)28/h2-13,26H,14H2,1H3,(H,22,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 202 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096468
(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)Show SMILES COC(=O)c1cccc(C(=O)NO)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C22H21N3O7S/c1-31-16-8-10-17(11-9-16)33(29,30)25(14-15-5-4-12-23-13-15)20-18(21(26)24-28)6-3-7-19(20)22(27)32-2/h3-13,28H,14H2,1-2H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096462
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cc(C)ccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-20(22(25)23-26)21(14-16)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 346 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096465
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(C)cc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-21(20(14-16)22(25)23-26)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 353 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096475
(2-(N-benzyl-4-methoxyphenylsulfonamido)-3-chloro-N...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(Cl)cccc1C(=O)NO Show InChI InChI=1S/C21H19ClN2O5S/c1-29-16-10-12-17(13-11-16)30(27,28)24(14-15-6-3-2-4-7-15)20-18(21(25)23-26)8-5-9-19(20)22/h2-13,26H,14H2,1H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096473
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cccc(C)c1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(21(16)22(25)23-26)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096474
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC)cccc1C(=O)NO Show InChI InChI=1S/C22H22N2O6S/c1-29-17-11-13-18(14-12-17)31(27,28)24(15-16-7-4-3-5-8-16)21-19(22(25)23-26)9-6-10-20(21)30-2/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096470
(2-(N-benzyl-4-methoxyphenylsulfonamido)-3-(dimethy...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cccc1C(=O)NO)N(C)C Show InChI InChI=1S/C23H25N3O5S/c1-25(2)21-11-7-10-20(23(27)24-28)22(21)26(16-17-8-5-4-6-9-17)32(29,30)19-14-12-18(31-3)13-15-19/h4-15,28H,16H2,1-3H3,(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 531 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096465
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(C)cc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-21(20(14-16)22(25)23-26)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 553 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096464
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxyb...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccccc1C(=O)NO Show InChI InChI=1S/C21H20N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-14,25H,15H2,1H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 555 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096467
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC(C)(C)C(=O)NO)cccc1C(=O)NO Show InChI InChI=1S/C25H27N3O8S/c1-25(2,24(30)27-32)36-21-11-7-10-20(23(29)26-31)22(21)28(16-17-8-5-4-6-9-17)37(33,34)19-14-12-18(35-3)13-15-19/h4-15,31-32H,16H2,1-3H3,(H,26,29)(H,27,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 597 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096464
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxyb...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccccc1C(=O)NO Show InChI InChI=1S/C21H20N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-14,25H,15H2,1H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 639 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50096464
(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxyb...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccccc1C(=O)NO Show InChI InChI=1S/C21H20N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-14,25H,15H2,1H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-9 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096473
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cccc(C)c1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(21(16)22(25)23-26)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 717 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096465
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(C)cc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-21(20(14-16)22(25)23-26)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 728 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096462
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cc(C)ccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-20(22(25)23-26)21(14-16)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 884 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50096462
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cc(C)ccc1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-8-13-20(22(25)23-26)21(14-16)24(15-17-6-4-3-5-7-17)30(27,28)19-11-9-18(29-2)10-12-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 982 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-13 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50096473
(2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1cccc(C)c1C(=O)NO Show InChI InChI=1S/C22H22N2O5S/c1-16-7-6-10-20(21(16)22(25)23-26)24(15-17-8-4-3-5-9-17)30(27,28)19-13-11-18(29-2)12-14-19/h3-14,26H,15H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
Inhibitory activity against Matrix metalloprotease-1 |
Bioorg Med Chem Lett 11: 235-8 (2001)
BindingDB Entry DOI: 10.7270/Q2TH8N78 |
More data for this
Ligand-Target Pair | |
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