Affinity Data by PubMed id=11229757

PubMed code 11229757

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 1/2/3 subunit alpha (Homo sapiens (Human))	BDBM50096974 (CHEMBL41306 \| N'-(2-Chloro-5-methylsulfanyl-phenyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibition of trypsin				Bioorg Med Chem Lett 11: 501-4 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7HVQ
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Homo sapiens (Human))	BDBM50096972 (CHEMBL422495 \| N'-(2-Chloro-5-methanesulfinyl-phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A protease				Bioorg Med Chem Lett 11: 501-4 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7HVQ
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Homo sapiens (Human))	BDBM50366770 (CHEMBL539841) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Neuronal sodium channel blocking activity by [14C]guanidinium flux assay				Bioorg Med Chem Lett 11: 501-4 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7HVQ
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Homo sapiens (Human))	BDBM50096975 (CHEMBL145968 \| N'-(2-Chloro-5-methylsulfanyl-pheny...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A protease				Bioorg Med Chem Lett 11: 501-4 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7HVQ
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Homo sapiens (Human))	BDBM50096975 (CHEMBL145968 \| N'-(2-Chloro-5-methylsulfanyl-pheny...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Inhibition of hepatitis c virus Non structural protein 3 protease/Non structural protein 4A protease				Bioorg Med Chem Lett 11: 501-4 (2001) BindingDB Entry DOI: 10.7270/Q2QJ7HVQ
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%