Affinity Data by PubMed id=11327589

PubMed code 11327589

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50072064 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50099002 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50098999 (5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3']bipyri...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50451344 (CHEMBL2303835) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50099001 (CHEMBL10042 \| [5-Chloro-3-(4-methanesulfonyl-pheny...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50072064 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of cytochrome P450 CYP3A4 in human liver microsomes				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50098999 (5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3']bipyri...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50099002 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50099001 (CHEMBL10042 \| [5-Chloro-3-(4-methanesulfonyl-pheny...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50072064 (5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50451344 (CHEMBL2303835) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%