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PubMed code 11425538

Compile data set for download or QSAR
Found 29 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101114
PNG
(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-sulfon...)
Show SMILES OS(=O)(=O)c1ccc2c(c1)[nH]c(=O)c1cc(F)ccc21
Show InChI InChI=1S/C13H8FNO4S/c14-7-1-3-9-10-4-2-8(20(17,18)19)6-12(10)15-13(16)11(9)5-7/h1-6H,(H,15,16)(H,17,18,19)
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n/an/a 10n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101129
PNG
(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Show SMILES Fc1ccc2c3ccc(cc3[nH]c(=O)c2c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C20H20FN3O3/c21-14-2-4-15-16-3-1-13(11-18(16)23-20(26)17(15)12-14)19(25)22-5-6-24-7-9-27-10-8-24/h1-4,11-12H,5-10H2,(H,22,25)(H,23,26)
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n/an/a 14n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101124
PNG
(CHEMBL298053 | sodium 8-fluoro-6-oxo-5,6-dihydroph...)
Show SMILES [O-]C(=O)c1ccc2c(c1)[nH]c(=O)c1cc(F)ccc21
Show InChI InChI=1S/C14H8FNO3/c15-8-2-4-9-10-3-1-7(14(18)19)5-12(10)16-13(17)11(9)6-8/h1-6H,(H,16,17)(H,18,19)/p-1
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101108
PNG
(CHEMBL289198 | Trimethyl-[(6-oxo-5,6-dihydro-phena...)
Show SMILES C[N+](C)(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1
Show InChI InChI=1S/C18H19N3O2/c1-21(2,3)11-17(22)19-12-8-9-16-15(10-12)13-6-4-5-7-14(13)18(23)20-16/h4-10H,11H2,1-3H3,(H-,19,20,22,23)/p+1
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101105
PNG
(6-Oxo-5,6-dihydro-phenanthridine-2-sulfonic acid (...)
Show SMILES O=c1[nH]c2ccc(cc2c2ccccc12)S(=O)(=O)NCCN1CCCCC1
Show InChI InChI=1S/C20H23N3O3S/c24-20-17-7-3-2-6-16(17)18-14-15(8-9-19(18)22-20)27(25,26)21-10-13-23-11-4-1-5-12-23/h2-3,6-9,14,21H,1,4-5,10-13H2,(H,22,24)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101104
PNG
(2-Chloro-N-(10-methyl-6-oxo-3-trifluoromethyl-5,6-...)
Show SMILES Cc1cccc2c1c1cc(NC(=O)CCl)c(cc1[nH]c2=O)C(F)(F)F
Show InChI InChI=1S/C17H12ClF3N2O2/c1-8-3-2-4-9-15(8)10-5-13(22-14(24)7-18)11(17(19,20)21)6-12(10)23-16(9)25/h2-6H,7H2,1H3,(H,22,24)(H,23,25)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101118
PNG
(6-Oxo-5,6-dihydro-phenanthridine-3-carboxylic acid...)
Show SMILES O=C(NCCN1CCOCC1)c1ccc2c(c1)[nH]c(=O)c1ccccc21
Show InChI InChI=1S/C20H21N3O3/c24-19(21-7-8-23-9-11-26-12-10-23)14-5-6-16-15-3-1-2-4-17(15)20(25)22-18(16)13-14/h1-6,13H,7-12H2,(H,21,24)(H,22,25)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101105
PNG
(6-Oxo-5,6-dihydro-phenanthridine-2-sulfonic acid (...)
Show SMILES O=c1[nH]c2ccc(cc2c2ccccc12)S(=O)(=O)NCCN1CCCCC1
Show InChI InChI=1S/C20H23N3O3S/c24-20-17-7-3-2-6-16(17)18-14-15(8-9-19(18)22-20)27(25,26)21-10-13-23-11-4-1-5-12-23/h2-3,6-9,14,21H,1,4-5,10-13H2,(H,22,24)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101103
PNG
(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Show SMILES COC(=O)c1ccc2c(c1)[nH]c(=O)c1cc(F)ccc21
Show InChI InChI=1S/C15H10FNO3/c1-20-15(19)8-2-4-11-10-5-3-9(16)7-12(10)14(18)17-13(11)6-8/h2-7H,1H3,(H,17,18)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101110
PNG
(2-Amino-10-methyl-3-trifluoromethyl-5H-phenanthrid...)
Show SMILES Cc1cccc2c1c1cc(N)c(cc1[nH]c2=O)C(F)(F)F
Show InChI InChI=1S/C15H11F3N2O/c1-7-3-2-4-8-13(7)9-5-11(19)10(15(16,17)18)6-12(9)20-14(8)21/h2-6H,19H2,1H3,(H,20,21)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101102
PNG
(CHEMBL48138 | sodium 6-oxo-5,6-dihydrophenanthridi...)
Show SMILES [O-]C(=O)c1ccc2c(c1)[nH]c(=O)c1ccccc21
Show InChI InChI=1S/C14H9NO3/c16-13-11-4-2-1-3-9(11)10-6-5-8(14(17)18)7-12(10)15-13/h1-7H,(H,15,16)(H,17,18)/p-1
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101116
PNG
(3-Fluoro-10-methyl-5H-phenanthridin-6-one | CHEMBL...)
Show SMILES Cc1cccc2c1c1ccc(F)cc1[nH]c2=O
Show InChI InChI=1S/C14H10FNO/c1-8-3-2-4-11-13(8)10-6-5-9(15)7-12(10)16-14(11)17/h2-7H,1H3,(H,16,17)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101126
PNG
(10-Methyl-2-nitro-3-trifluoromethyl-5H-phenanthrid...)
Show SMILES Cc1cccc2c1c1cc(c(cc1[n-]c2=[OH+])C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C15H9F3N2O3/c1-7-3-2-4-8-13(7)9-5-12(20(22)23)10(15(16,17)18)6-11(9)19-14(8)21/h2-6H,1H3,(H,19,21)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101125
PNG
(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Show SMILES Fc1ccc2c3ccc(cc3[nH]c(=O)c2c1)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C22H17FN2O2/c23-16-7-9-17-18-8-6-15(12-20(18)25-22(27)19(17)13-16)21(26)24-11-10-14-4-2-1-3-5-14/h1-9,12-13H,10-11H2,(H,24,26)(H,25,27)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101127
PNG
(2-Nitro-5H-phenanthridin-6-one | CHEMBL48391)
Show SMILES [O-][N+](=O)c1ccc2[n-]c(=[OH+])c3ccccc3c2c1
Show InChI InChI=1S/C13H8N2O3/c16-13-10-4-2-1-3-9(10)11-7-8(15(17)18)5-6-12(11)14-13/h1-7H,(H,14,16)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101115
PNG
(2,3-Diamino-5H-phenanthridin-6-one | CHEMBL45764)
Show SMILES Nc1cc2[nH]c(=O)c3ccccc3c2cc1N
Show InChI InChI=1S/C13H11N3O/c14-10-5-9-7-3-1-2-4-8(7)13(17)16-12(9)6-11(10)15/h1-6H,14-15H2,(H,16,17)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50200497
PNG
(2-Amino-5H-phenanthridin-6-one | 2-aminophenanthri...)
Show SMILES Nc1ccc2[nH]c(=O)c3ccccc3c2c1
Show InChI InChI=1S/C13H10N2O/c14-8-5-6-12-11(7-8)9-3-1-2-4-10(9)13(16)15-12/h1-7H,14H2,(H,15,16)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101113
PNG
(6-Oxo-5,6-dihydro-phenanthridine-3-carboxylic acid...)
Show SMILES COC(=O)c1ccc2c(c1)[nH]c(=O)c1ccccc21
Show InChI InChI=1S/C15H11NO3/c1-19-15(18)9-6-7-11-10-4-2-3-5-12(10)14(17)16-13(11)8-9/h2-8H,1H3,(H,16,17)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101120
PNG
(CHEMBL297175 | Trimethyl-[(3-methyl-6-oxo-5,6-dihy...)
Show SMILES Cc1cc2[nH]c(=O)c3ccccc3c2cc1NC(=O)C[N+](C)(C)C
Show InChI InChI=1S/C19H21N3O2/c1-12-9-17-15(10-16(12)20-18(23)11-22(2,3)4)13-7-5-6-8-14(13)19(24)21-17/h5-10H,11H2,1-4H3,(H-,20,21,23,24)/p+1
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101121
PNG
(3,8-Dichloro-5H-phenanthridin-6-one | CHEMBL298450)
Show SMILES Clc1ccc2c(c1)[nH]c(=O)c1cc(Cl)ccc21
Show InChI InChI=1S/C13H7Cl2NO/c14-7-1-3-9-10-4-2-8(15)6-12(10)16-13(17)11(9)5-7/h1-6H,(H,16,17)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101123
PNG
(4-Amino-5H-phenanthridin-6-one | CHEMBL298064)
Show SMILES Nc1cccc2c3ccccc3c(=O)[nH]c12
Show InChI InChI=1S/C13H10N2O/c14-11-7-3-6-9-8-4-1-2-5-10(8)13(16)15-12(9)11/h1-7H,14H2,(H,15,16)
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Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM27500
PNG
(5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...)
Show SMILES O=c1[nH]c2ccccc2c2ccccc12
Show InChI InChI=1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)
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n/an/a 520n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101119
PNG
(6-Oxo-5,6-dihydro-phenanthridine-1-carboxylic acid...)
Show SMILES OC(=O)c1cccc2[nH]c(=O)c3ccccc3c12
Show InChI InChI=1S/C14H9NO3/c16-13-9-5-2-1-4-8(9)12-10(14(17)18)6-3-7-11(12)15-13/h1-7H,(H,15,16)(H,17,18)
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n/an/a 2.01E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101109
PNG
(3,8-Diamino-5H-phenanthridin-6-one | CHEMBL47840)
Show SMILES Nc1ccc2c(c1)[nH]c(=O)c1cc(N)ccc21
Show InChI InChI=1S/C13H11N3O/c14-7-1-3-9-10-4-2-8(15)6-12(10)16-13(17)11(9)5-7/h1-6H,14-15H2,(H,16,17)
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n/an/a 3.26E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101117
PNG
(4-Nitro-5H-phenanthridin-6-one | CHEMBL45904)
Show SMILES [O-][N+](=O)c1cccc2c1[nH]c(=O)c1ccccc21
Show InChI InChI=1S/C13H8N2O3/c16-13-10-5-2-1-4-8(10)9-6-3-7-11(15(17)18)12(9)14-13/h1-7H,(H,14,16)
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n/an/a 6.10E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101111
PNG
(6-Oxo-5,6-dihydro-phenanthridine-2-sulfonic acid (...)
Show SMILES O=c1[nH]c2ccc(cc2c2ccccc12)S(=O)(=O)NCC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H22N2O3S/c30-27-23-14-8-7-13-22(23)24-17-21(15-16-26(24)29-27)33(31,32)28-18-25(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-17,25,28H,18H2,(H,29,30)
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n/an/a 1.40E+4n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101122
PNG
(3,8-Dinitro-5H-phenanthridin-6-one | CHEMBL47846)
Show SMILES [O-][N+](=O)c1ccc2c(c1)[nH]c(=O)c1cc(ccc21)[N+]([O-])=O
Show InChI InChI=1S/C13H7N3O5/c17-13-11-5-7(15(18)19)1-3-9(11)10-4-2-8(16(20)21)6-12(10)14-13/h1-6H,(H,14,17)
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n/an/a 3.50E+4n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101130
PNG
(6-Oxo-5,6-dihydro-phenanthridine-10-carboxylic aci...)
Show SMILES OC(=O)c1cccc2c1c1ccccc1[nH]c2=O
Show InChI InChI=1S/C14H9NO3/c16-13-9-5-3-6-10(14(17)18)12(9)8-4-1-2-7-11(8)15-13/h1-7H,(H,15,16)(H,17,18)
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n/an/a>6.00E+4n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50101107
PNG
(CHEMBL46267 | disodium 6-oxo-5,6-dihydrophenanthri...)
Show SMILES [O-]S(=O)(=O)c1ccc2c(c1)[nH]c(=O)c1cc(ccc21)S([O-])(=O)=O
Show InChI InChI=1S/C13H9NO7S2/c15-13-11-5-7(22(16,17)18)1-3-9(11)10-4-2-8(23(19,20)21)6-12(10)14-13/h1-6H,(H,14,15)(H,16,17,18)(H,19,20,21)/p-2
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n/an/a>1.00E+5n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1

Bioorg Med Chem Lett 11: 1687-90 (2001)


BindingDB Entry DOI: 10.7270/Q2348KWN
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%