Affinity Data by PubMed id=11426832

PubMed code 11426832

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of E1S uptake in OAT3-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	7.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of E1S uptake in OAT3-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of E1S uptake in OAT3-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	2.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of E1S uptake in OAT3-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	1.47E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells				Eur J Pharmacol 419: 113-20 (2001) BindingDB Entry DOI: 10.7270/Q2S183SP
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%