Affinity Data by PubMed id=11428921

PubMed code 11428921

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-P receptor (Homo sapiens (Human))	BDBM50101417 (CHEMBL539928 \| [1-Dimethylaminomethyl-2-(1H-indol-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101415 (CHEMBL306089 \| [2-(1H-Indol-3-yl)-1-methoxymethyl-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101420 (CHEMBL76501 \| [2-(1H-Indol-3-yl)-1-(1-phenyl-ethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101414 (CHEMBL76455 \| [1-(1H-Indol-3-ylmethyl)-1-(1-phenyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101419 (CHEMBL77684 \| [1-(1H-Indol-3-ylmethyl)-1-(1-phenyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101416 (CHEMBL307488 \| [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.05	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101418 (CHEMBL72895 \| [1-(1H-Indol-3-ylmethyl)-3-methyl-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.79	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description Inhibition of specific binding at tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101417 (CHEMBL539928 \| [1-Dimethylaminomethyl-2-(1H-indol-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description In vitro affinity for specific binding at Gerbil tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50101416 (CHEMBL307488 \| [(R)-2-(3H-Indol-3-yl)-1-methyl-1-(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge University Forvie Site Curated by ChEMBL					Assay Description In vitro affinity for specific binding at Gerbil tachykinin receptor 1				J Med Chem 44: 2276-85 (2001) BindingDB Entry DOI: 10.7270/Q2XS5TN8
Cambridge University Forvie Site Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%