Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102311 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102309 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102307 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102308 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102312 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 267 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102310 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 504 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102306 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50102313 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 2 in 143.98.2 from human osteosarcoma cells | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102311 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102312 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102313 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102306 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102309 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102307 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102310 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Homo sapiens (Human)) | BDBM50102308 (3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
J. Uriach & Cía. S.A. Curated by ChEMBL | Assay Description Inhibition of Prostaglandin G/H synthase 1 in U-937 cells from human histiocytic lymphoma | J Med Chem 44: 350-61 (2001) BindingDB Entry DOI: 10.7270/Q29W0DSN | |||||||||||
More data for this Ligand-Target Pair |