Affinity Data by PubMed id=11527727

PubMed code 11527727

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103820 (CHEMBL309058 \| [2-(3-Hydroxy-4-methoxy-phenyl)-thi...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50005480 ((-)-combretastatin \| (Z)-3'-hydroxy-3,4,4',5-tetra...) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103821 (CHEMBL310038 \| [2-(3-Hydroxy-4-methoxy-phenyl)-6-m...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103822 (2-Methoxy-5-[3-(3,4,5-trimethoxy-phenyl)-4,5-dihyd...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103819 (5-{Hydroxy-[6-methoxy-2-(3,4,5-trimethoxy-phenyl)-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103824 (5-{Hydroxy-[2-(3,4,5-trimethoxy-phenyl)-thiophen-3...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103823 ((6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-y...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50103825 ((3-Hydroxy-4-methoxy-phenyl)-[2-(3,4,5-trimethoxy-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Australian National University Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of tubulin polymerization				Bioorg Med Chem Lett 11: 2341-3 (2001) BindingDB Entry DOI: 10.7270/Q2WH2P8G
Australian National University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%