Affinity Data by PubMed id=11741469

PubMed code 11741469

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor 1 (Mus musculus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity towards GluR1 receptor from rat brain				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Rattus norvegicus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB PubMed	218	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity towards Ionotropic glutamate receptor AMPA 2 from rat brain				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 4 (Rattus norvegicus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB PubMed	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity towards GluR4 receptor from rat brain				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 3 (RAT)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity towards Ionotropic glutamate receptor AMPA 3 from rat brain				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 3 (RAT)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	2.24E+5	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description The potency at recombinant rat AMPA-R was measured on Ionotropic glutamate receptor AMPA 3 expressed in Xenopus Laevis oocytes				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 4 (Rattus norvegicus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB PubMed	n/a	n/a	n/a	n/a	3.43E+4	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description The potency at recombinant rat AMPA-R was measured on GluR4 receptor expressed in Xenopus Laevis oocytes				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Mus musculus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.49E+4	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description The potency at recombinant rat AMPA-R was measured on GluR1 receptor expressed in Xenopus Laevis oocytes				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Rattus norvegicus)	BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB PubMed	n/a	n/a	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a
Universita' degli Studi di Siena Curated by ChEMBL					Assay Description The potency at recombinant rat AMPA-R was measured on receptor Ionotropic glutamate receptor AMPA 2 expressed in Xenopus Laevis oocytes				J Med Chem 44: 4501-4 (2001) BindingDB Entry DOI: 10.7270/Q2MC8Z9N
Universita' degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%