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PubMed code 11909705

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111082
PNG
(9-Chloro-2-phenyl-3,4,5,6-tetrahydro-1,3-diaza-ben...)
Show SMILES Clc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccccc1
Show InChI InChI=1S/C18H15ClN2/c19-14-10-9-12-7-4-8-16-17(15(12)11-14)21-18(20-16)13-5-2-1-3-6-13/h1-3,5-6,9-11H,4,7-8H2,(H,20,21)
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n/an/a 1.70n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111079
PNG
(9-Methyl-2-pyridin-3-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Cc1ccc2CCCc3[nH]c(nc3-c2c1)-c1cccnc1
Show InChI InChI=1S/C18H17N3/c1-12-7-8-13-4-2-6-16-17(15(13)10-12)21-18(20-16)14-5-3-9-19-11-14/h3,5,7-11H,2,4,6H2,1H3,(H,20,21)
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n/an/a 2.30n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111085
PNG
(2-Phenyl-3,4,5,6-tetrahydro-1,3-diaza-benzo[e]azul...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1ccccc1
Show InChI InChI=1S/C18H16N2/c1-2-8-14(9-3-1)18-19-16-12-6-10-13-7-4-5-11-15(13)17(16)20-18/h1-5,7-9,11H,6,10,12H2,(H,19,20)
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n/an/a 5.80n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111083
PNG
(9-Methoxy-2-pyridin-3-yl-3,4,5,6-tetrahydro-1,3-di...)
Show SMILES COc1ccc2CCCc3[nH]c(nc3-c2c1)-c1cccnc1
Show InChI InChI=1S/C18H17N3O/c1-22-14-8-7-12-4-2-6-16-17(15(12)10-14)21-18(20-16)13-5-3-9-19-11-13/h3,5,7-11H,2,4,6H2,1H3,(H,20,21)
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n/an/a 6.30n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111089
PNG
(9-Methyl-2-pyridin-4-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Cc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccncc1
Show InChI InChI=1S/C18H17N3/c1-12-5-6-13-3-2-4-16-17(15(13)11-12)21-18(20-16)14-7-9-19-10-8-14/h5-11H,2-4H2,1H3,(H,20,21)
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n/an/a 6.40n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111092
PNG
(9-Fluoro-2-pyridin-3-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Fc1ccc2CCCc3[nH]c(nc3-c2c1)-c1cccnc1
Show InChI InChI=1S/C17H14FN3/c18-13-7-6-11-3-1-5-15-16(14(11)9-13)21-17(20-15)12-4-2-8-19-10-12/h2,4,6-10H,1,3,5H2,(H,20,21)
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n/an/a 6.40n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111094
PNG
(2-Pyridin-3-yl-3,4,5,6-tetrahydro-1,3-diaza-benzo[...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1cccnc1
Show InChI InChI=1S/C17H15N3/c1-2-8-14-12(5-1)6-3-9-15-16(14)20-17(19-15)13-7-4-10-18-11-13/h1-2,4-5,7-8,10-11H,3,6,9H2,(H,19,20)
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n/an/a 7.30n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111080
PNG
(9-Fluoro-2-pyridin-4-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Fc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccncc1
Show InChI InChI=1S/C17H14FN3/c18-13-5-4-11-2-1-3-15-16(14(11)10-13)21-17(20-15)12-6-8-19-9-7-12/h4-10H,1-3H2,(H,20,21)
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n/an/a 13n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111095
PNG
(9-Methoxy-2-pyridin-4-yl-3,4,5,6-tetrahydro-1,3-di...)
Show SMILES COc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccncc1
Show InChI InChI=1S/C18H17N3O/c1-22-14-6-5-12-3-2-4-16-17(15(12)11-14)21-18(20-16)13-7-9-19-10-8-13/h5-11H,2-4H2,1H3,(H,20,21)
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n/an/a 13n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111081
PNG
(2-Pyridin-4-yl-3,4,5,6-tetrahydro-1,3-diaza-benzo[...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1ccncc1
Show InChI InChI=1S/C17H15N3/c1-2-6-14-12(4-1)5-3-7-15-16(14)20-17(19-15)13-8-10-18-11-9-13/h1-2,4,6,8-11H,3,5,7H2,(H,19,20)
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n/an/a 20n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111096
PNG
(9-Methoxy-2-phenyl-3,4,5,6-tetrahydro-1,3-diaza-be...)
Show SMILES COc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccccc1
Show InChI InChI=1S/C19H18N2O/c1-22-15-11-10-13-8-5-9-17-18(16(13)12-15)21-19(20-17)14-6-3-2-4-7-14/h2-4,6-7,10-12H,5,8-9H2,1H3,(H,20,21)
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n/an/a 25n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111078
PNG
(9-Methyl-2-pyridin-2-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Cc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccccn1
Show InChI InChI=1S/C18H17N3/c1-12-8-9-13-5-4-7-15-17(14(13)11-12)21-18(20-15)16-6-2-3-10-19-16/h2-3,6,8-11H,4-5,7H2,1H3,(H,20,21)
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n/an/a 32n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111088
PNG
(9-Fluoro-2-pyridin-2-yl-3,4,5,6-tetrahydro-1,3-dia...)
Show SMILES Fc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccccn1
Show InChI InChI=1S/C17H14FN3/c18-12-8-7-11-4-3-6-14-16(13(11)10-12)21-17(20-14)15-5-1-2-9-19-15/h1-2,5,7-10H,3-4,6H2,(H,20,21)
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n/an/a 46n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111090
PNG
(8-Methoxy-2-phenyl-4,5-dihydro-3H-naphtho[1,2-d]im...)
Show SMILES COc1ccc2CCc3[nH]c(nc3-c2c1)-c1ccccc1
Show InChI InChI=1S/C18H16N2O/c1-21-14-9-7-12-8-10-16-17(15(12)11-14)20-18(19-16)13-5-3-2-4-6-13/h2-7,9,11H,8,10H2,1H3,(H,19,20)
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n/an/a 52n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111091
PNG
(2-Pyridin-2-yl-3,4,5,6-tetrahydro-1,3-diaza-benzo[...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1ccccn1
Show InChI InChI=1S/C17H15N3/c1-2-8-13-12(6-1)7-5-10-14-16(13)20-17(19-14)15-9-3-4-11-18-15/h1-4,6,8-9,11H,5,7,10H2,(H,19,20)
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n/an/a 110n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111087
PNG
(9-Methoxy-2-pyridin-2-yl-3,4,5,6-tetrahydro-1,3-di...)
Show SMILES COc1ccc2CCCc3[nH]c(nc3-c2c1)-c1ccccn1
Show InChI InChI=1S/C18H17N3O/c1-22-13-9-8-12-5-4-7-15-17(14(12)11-13)21-18(20-15)16-6-2-3-10-19-16/h2-3,6,8-11H,4-5,7H2,1H3,(H,20,21)
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n/an/a 110n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111086
PNG
(3-(5-Methyl-2-phenyl-1H-imidazol-4-yl)-pyridine | ...)
Show SMILES Cc1[nH]c(nc1-c1cccnc1)-c1ccccc1
Show InChI InChI=1S/C15H13N3/c1-11-14(13-8-5-9-16-10-13)18-15(17-11)12-6-3-2-4-7-12/h2-10H,1H3,(H,17,18)
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n/an/a 427n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111093
PNG
(2-(1H-Imidazol-4-yl)-3,4,5,6-tetrahydro-1,3-diaza-...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2C1)-c1c[nH]cn1
Show InChI InChI=1S/C15H14N4/c1-2-6-11-10(4-1)5-3-7-12-14(11)19-15(18-12)13-8-16-9-17-13/h1-2,4,6,8-9H,3,5,7H2,(H,16,17)(H,18,19)
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n/an/a 570n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5


(Homo sapiens (Human))		BDBM50111084
PNG
(2-Phenyl-4,5-dihydro-3H-6-oxa-1,3-diaza-benzo[e]az...)
Show SMILES C1Cc2[nH]c(nc2-c2ccccc2O1)-c1ccccc1
Show InChI InChI=1S/C17H14N2O/c1-2-6-12(7-3-1)17-18-14-10-11-20-15-9-5-4-8-13(15)16(14)19-17/h1-9H,10-11H2,(H,18,19)
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n/an/a 6.10E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Concentration that inhibited 50% of binding of 125 I -PYY ligand to human Neuropeptide Y receptor type 5

Bioorg Med Chem Lett 12: 1009-11 (2002)


BindingDB Entry DOI: 10.7270/Q2J102G1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%