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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8552 (2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8550 (2-{[(3-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8555 (methyl 3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8541 (N-[2-(2-fluorophenyl)ethyl]-2-[4-({[5-(pyridin-4-y...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8554 (2-{[(3-fluorophenyl)methyl]sulfanyl}-5-(pyridin-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8548 (2-(benzylsulfanyl)-5-(pyridin-4-yl)-1,3,4-oxadiazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8543 (2-[4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulf...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8542 (2-[4-({[5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl]sul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8551 (2-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8547 (4-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8549 (2-[(2-phenylethyl)sulfanyl]-5-(pyridin-4-yl)-1,3,4...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8553 (2-{[(4-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.98E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8556 (3-({[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfany...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.35E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8546 (2-[4-({[5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl]sul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8557 (2-({[3-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]methy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8545 (2-[4-({[5-(pyridin-3-yl)-1,3,4-thiadiazol-2-yl]sul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM8544 (2-[4-({[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sul...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Novo Nordisk A/S | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | Bioorg Med Chem Lett 12: 1525-8 (2002) Article DOI: 10.1016/s0960-894x(02)00169-5 BindingDB Entry DOI: 10.7270/Q2251GDH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
