Affinity Data by PubMed id=12365460

PubMed code 12365460

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85585 (2-Styrylchromone derivate, 3c) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85584 (2-Styrylchromone derivate, 3b) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85579 (2-Styrylchromone derivate, 1d) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85583 (2-Styrylchromone derivate, 3a) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.36E+3	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM35440 (ALLOPURINOL \| MLS000069453 \| SMR000059083 \| cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.43E+3	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85582 (2-Styrylchromone derivate, 2c) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.46E+3	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85578 (2-Styrylchromone derivate, 1c) Show SMILES Oc1ccc2c(c1)oc(\C=C\c1ccccc1)cc2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85581 (2-Styrylchromone derivate, 2b) Show SMILES Oc1ccc(\C=C\c2cc(=O)c3ccc(O)cc3o2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85577 (2-Styrylchromone derivate, 1b) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.21E+4	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85580 (2-Styrylchromone derivate, 2a) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.74E+4	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM85576 (2-Styrylchromone derivate, 1a \| cid_754332) Show SMILES O=c1cc(\C=C\c2ccccc2)oc2ccccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.8	25
University of Porto-Rua Anibal Cunha					Assay Description The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...				J Enzyme Inhib Med Chem 17: 45-8 (2002) Article DOI: 10.1080/14756360290019944 BindingDB Entry DOI: 10.7270/Q29S1PKM
University of Porto-Rua Anibal Cunha					More data for this Ligand-Target Pair

* indicates data uncertainty>20%