Affinity Data by PubMed id=12392741

PubMed code 12392741

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50080081 (3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50120573 ((S)-5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50120571 (5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phenyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50120572 (3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 2 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50120573 ((S)-5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50120571 (5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phenyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50080081 (3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-dime...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibitory potency of the compound was determined against Prostaglandin G/H synthase 1 in human whole blood assay				Bioorg Med Chem Lett 12: 3317-20 (2002) BindingDB Entry DOI: 10.7270/Q2FQ9VZ6
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%