Affinity Data by PubMed id=12408708

PubMed code 12408708

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM22985 (Aralen \| CHEMBL76 \| CHLOROQUINE PHOSPHATE \| Chloro...) Show SMILES CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120736 ((2-Piperidin-1-yl-ethyl)-(7-trifluoromethyl-quinol...) Show SMILES FC(F)(F)c1ccc2c(NCCN3CCCCC3)ccnc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120735 (CHEMBL146617 \| N-(7-chloroquinolin-4-yl)-N-tert-bu...) Show SMILES CC(C)(C)NCCNc1ccnc2cc(Cl)ccc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120737 (CHEMBL148195 \| N-tert-Butyl-N'-(7-trifluoromethyl-...) Show SMILES CC(C)(C)NCCNc1ccnc2cc(ccc12)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120738 ((7-Chloro-quinolin-4-yl)-(2-pyrrolidin-1-yl-ethyl)...) Show SMILES Clc1ccc2c(NCCN3CCCC3)ccnc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120734 ((7-Chloro-quinolin-4-yl)-(2-piperidin-1-yl-ethyl)-...) Show SMILES Clc1ccc2c(NCCN3CCCCC3)ccnc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50120739 ((7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-...) Show SMILES Clc1ccc2c(NCCN3CCOCC3)ccnc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Liverpool Curated by ChEMBL					Assay Description Inhibition of beta-hematin formation				J Med Chem 45: 4975-83 (2002) BindingDB Entry DOI: 10.7270/Q2P55PQ4
The University of Liverpool Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%