Found 26 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230620
(CHEMBL9585)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c1C Show InChI InChI=1S/C17H15F4N3O3S/c1-9-13(22-6-5-14(9)26-2)8-28(25)16-23-11-4-3-10(7-12(11)24-16)27-17(20,21)15(18)19/h3-7,15H,8H2,1-2H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50070208
(A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...)Show SMILES Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230610
(CHEMBL9890)Show SMILES COc1c(C)cnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1C Show InChI InChI=1S/C17H17F2N3O3S/c1-9-7-20-14(10(2)15(9)24-3)8-26(23)17-21-12-5-4-11(25-16(18)19)6-13(12)22-17/h4-7,16H,8H2,1-3H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50103597
(Antra | CHEBI:77260 | H 168/68 | H-168/68 | Losec ...)Show SMILES COc1ccc2[nH]c(nc2c1)[S+]([O-])Cc1ncc(C)c(OC)c1C | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| MMDB
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230584
(CHEMBL9443)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1C Show InChI InChI=1S/C16H15F2N3O3S/c1-9-13(19-6-5-14(9)23-2)8-25(22)16-20-11-4-3-10(24-15(17)18)7-12(11)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) | PDB
KEGG
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230585
(CHEMBL9856)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OCC(F)(F)F)ccc3[nH]2)c1C Show InChI InChI=1S/C17H16F3N3O3S/c1-10-14(21-6-5-15(10)25-2)8-27(24)16-22-12-4-3-11(7-13(12)23-16)26-9-17(18,19)20/h3-7H,8-9H2,1-2H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230605
(CHEMBL273395)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OCC(F)(F)F)ccc3[nH]2)c1OC Show InChI InChI=1S/C17H16F3N3O4S/c1-25-14-5-6-21-13(15(14)26-2)8-28(24)16-22-11-4-3-10(7-12(11)23-16)27-9-17(18,19)20/h3-7H,8-9H2,1-2H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50241342
(5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl)...)Show SMILES COc1ccnc(CS(=O)c2nc3ccc(OC(F)F)cc3[nH]2)c1OC Show InChI InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| DrugBank
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230621
(CHEMBL9539)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc4OC(F)(F)Oc4cc3[nH]2)c1C Show InChI InChI=1S/C16H13F2N3O4S/c1-8-11(19-4-3-12(8)23-2)7-26(22)15-20-9-5-13-14(6-10(9)21-15)25-16(17,18)24-13/h3-6H,7H2,1-2H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230608
(CHEMBL10075)Show SMILES COc1cc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)ncc1C Show InChI InChI=1S/C17H15F4N3O3S/c1-9-7-22-10(5-14(9)26-2)8-28(25)16-23-12-4-3-11(6-13(12)24-16)27-17(20,21)15(18)19/h3-7,15H,8H2,1-2H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230607
(CHEMBL275945)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c1 Show InChI InChI=1S/C16H13F4N3O3S/c1-25-10-4-5-21-9(6-10)8-27(24)15-22-12-3-2-11(7-13(12)23-15)26-16(19,20)14(17)18/h2-7,14H,8H2,1H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230616
(CHEMBL10060)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1 Show InChI InChI=1S/C15H13F2N3O3S/c1-22-10-4-5-18-9(6-10)8-24(21)15-19-12-3-2-11(23-14(16)17)7-13(12)20-15/h2-7,14H,8H2,1H3,(H,19,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230613
(CHEMBL9427)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)c(OC)cc3[nH]2)c1C Show InChI InChI=1S/C17H17F2N3O4S/c1-9-12(20-5-4-13(9)24-2)8-27(23)17-21-10-6-14(25-3)15(26-16(18)19)7-11(10)22-17/h4-7,16H,8H2,1-3H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230617
(CHEMBL9800)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc4OC(F)(F)Oc4cc3[nH]2)c1OC Show InChI InChI=1S/C16H13F2N3O5S/c1-23-11-3-4-19-10(14(11)24-2)7-27(22)15-20-8-5-12-13(6-9(8)21-15)26-16(17,18)25-12/h3-6H,7H2,1-2H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230583
(CHEMBL9959)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc4OC(F)(F)Oc4cc3[nH]2)c1 Show InChI InChI=1S/C15H11F2N3O4S/c1-22-9-2-3-18-8(4-9)7-25(21)14-19-10-5-12-13(6-11(10)20-14)24-15(16,17)23-12/h2-6H,7H2,1H3,(H,19,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230606
(CHEMBL9430)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c(C)c1OC Show InChI InChI=1S/C17H17F2N3O4S/c1-9-13(20-7-14(24-2)15(9)25-3)8-27(23)17-21-11-5-4-10(26-16(18)19)6-12(11)22-17/h4-7,16H,8H2,1-3H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230615
(CHEMBL9992)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc(OCC(F)(F)F)ccc3[nH]2)c(C)c1OC Show InChI InChI=1S/C18H18F3N3O4S/c1-10-14(22-7-15(26-2)16(10)27-3)8-29(25)17-23-12-5-4-11(6-13(12)24-17)28-9-18(19,20)21/h4-7H,8-9H2,1-3H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230611
(CHEMBL273600)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(F)c(OC(F)F)cc3[nH]2)c1C Show InChI InChI=1S/C16H14F3N3O3S/c1-8-12(20-4-3-13(8)24-2)7-26(23)16-21-10-5-9(17)14(25-15(18)19)6-11(10)22-16/h3-6,15H,7H2,1-2H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230618
(CHEMBL9694)Show SMILES COc1cc2[nH]c(nc2cc1OC(F)F)[S+]([O-])Cc1nccc(OC)c1OC Show InChI InChI=1S/C17H17F2N3O5S/c1-24-12-4-5-20-11(15(12)26-3)8-28(23)17-21-9-6-13(25-2)14(27-16(18)19)7-10(9)22-17/h4-7,16H,8H2,1-3H3,(H,21,22) | PDB
KEGG
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DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230603
(CHEMBL9638)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c1OC Show InChI InChI=1S/C17H15F4N3O4S/c1-26-13-5-6-22-12(14(13)27-2)8-29(25)16-23-10-4-3-9(7-11(10)24-16)28-17(20,21)15(18)19/h3-7,15H,8H2,1-2H3,(H,23,24) | PDB
KEGG
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antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230612
(CHEMBL9845)Show SMILES COc1ccnc(C[S+]([O-])c2nc3cc(F)c(OC(F)F)cc3[nH]2)c1OC Show InChI InChI=1S/C16H14F3N3O4S/c1-24-12-3-4-20-11(14(12)25-2)7-27(23)16-21-9-5-8(17)13(26-15(18)19)6-10(9)22-16/h3-6,15H,7H2,1-2H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230609
(CHEMBL10061)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c(C)c1OC Show InChI InChI=1S/C18H17F4N3O4S/c1-9-13(23-7-14(27-2)15(9)28-3)8-30(26)17-24-11-5-4-10(6-12(11)25-17)29-18(21,22)16(19)20/h4-7,16H,8H2,1-3H3,(H,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230614
(CHEMBL9658)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc4OC(F)(F)Oc4cc3[nH]2)c(C)c1OC Show InChI InChI=1S/C17H15F2N3O5S/c1-8-11(20-6-14(24-2)15(8)25-3)7-28(23)16-21-9-4-12-13(5-10(9)22-16)27-17(18,19)26-12/h4-6H,7H2,1-3H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230604
(CHEMBL10070)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)cc1OC Show InChI InChI=1S/C17H15F4N3O4S/c1-26-13-5-9(22-7-14(13)27-2)8-29(25)16-23-11-4-3-10(6-12(11)24-16)28-17(20,21)15(18)19/h3-7,15H,8H2,1-2H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230582
(CHEMBL9786)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)cc1OC Show InChI InChI=1S/C16H15F2N3O4S/c1-23-13-5-9(19-7-14(13)24-2)8-26(22)16-20-11-4-3-10(25-15(17)18)6-12(11)21-16/h3-7,15H,8H2,1-2H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
Potassium-transporting ATPase alpha chain 1/subunit beta
(Homo sapiens (Human)) | BDBM50230619
(CHEMBL9768)Show SMILES COc1cnc(C[S+]([O-])c2nc3cc4OC(F)(F)Oc4cc3[nH]2)cc1OC Show InChI InChI=1S/C16H13F2N3O5S/c1-23-11-3-8(19-6-14(11)24-2)7-27(22)15-20-9-4-12-13(5-10(9)21-15)26-16(17,18)25-12/h3-6H,7H2,1-2H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Byk Gulden Pharmaceuticals
Curated by ChEMBL
| Assay Description
In vitro evaluation for the inhibition of H+/K+ ATPase at pH < 3 in the gastric glands of isolated rabbit stomach. |
J Med Chem 35: 1049-57 (1992)
BindingDB Entry DOI: 10.7270/Q2QJ7KJH |
More data for this
Ligand-Target Pair | |
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