Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003237 (2,2-Dimethyl-butyric acid 2-(1-hydroxy-ethyl)-8-[2...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003236 (2,2-Dimethyl-butyric acid 2-hydroxymethyl-8-[2-(4-...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003240 (2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003239 (2,2-Dimethyl-butyric acid 2-hydroxy-8-[2-(4-hydrox...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003235 (2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50003241 (2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-te...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50011036 ((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description The compound was tested in vitro for inhibitory activity against HMG-CoA reductase | J Med Chem 35: 3813-21 (1992) BindingDB Entry DOI: 10.7270/Q27M06VP | |||||||||||
More data for this Ligand-Target Pair |