Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heat shock protein HSP 90-alpha/90-beta (Homo sapiens (Human)) | BDBM15359 ((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Binding affinity towards Heat shock protein HSP 90-alpha inhibitor | Bioorg Med Chem Lett 13: 3975-8 (2003) BindingDB Entry DOI: 10.7270/Q2W958KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock protein HSP 90-alpha/90-beta (Homo sapiens (Human)) | BDBM15374 (9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Memorial Sloan-Kettering Cancer Center Curated by ChEMBL | Assay Description Binding affinity towards Heat shock protein HSP 90-alpha inhibitor | Bioorg Med Chem Lett 13: 3975-8 (2003) BindingDB Entry DOI: 10.7270/Q2W958KM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |