Affinity Data by PubMed id=14643318

PubMed code 14643318

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase (Homo sapiens (Human))	BDBM50222441 (CHEMBL114237) Show SMILES BrCC(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222416 (CHEMBL344920) Show SMILES BrCC(=O)NCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222448 (CHEMBL137278) Show SMILES COC(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222452 (CHEMBL137100 \| Octanedioic acid phenylamide pyridi...) Show SMILES O=C(CCCCCCC(=O)Nc1ccccn1)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222409 (CHEMBL137333) Show SMILES OCCNC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222443 (CHEMBL264784) Show SMILES O=C(CCCCCCN(CC#C)CC#C)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222449 (CHEMBL344475) Show SMILES NCCNC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222412 (CHEMBL341701) Show SMILES O=C(CCCCCCNCC#C)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222446 (CHEMBL137672) Show SMILES O\N=C(\CCCCCCC(=O)Nc1ccccc1)c1ccccn1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222444 (CHEMBL137036) Show SMILES ClC(Cl)(Cl)C(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222415 (CHEMBL136992) Show SMILES CCOC(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222451 (CHEMBL343377 \| Octanedioic acid phenylamide thiazo...) Show SMILES O=C(CCCCCCC(=O)Nc1ccccc1)Nc1nccs1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222410 (7-Ureido-Heptanoic Acid Phenylamide \| CHEMBL137216) Show SMILES NC(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222442 (CHEMBL423356) Show SMILES OCCOC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222453 (CHEMBL137695) Show SMILES O=C(CCCCCCC(=O)c1ccccn1)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222454 (CHEMBL137003) Show SMILES FC(F)(F)C(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222414 (BML-210 \| CHEBI:61077 \| CHEMBL324053) Show SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222447 (CHEMBL138381) Show SMILES BrCC(=O)NCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222413 (CHEMBL112539) Show SMILES NNC(=O)NCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222450 (CHEMBL137519) Show SMILES BrCC(=O)NCCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222445 (CHEMBL422460) Show SMILES NNC(=O)NCCCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50222411 (CHEMBL136792) Show SMILES NNC(=O)NCCCCC(=O)Nc1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extract				Bioorg Med Chem Lett 13: 4321-6 (2003) BindingDB Entry DOI: 10.7270/Q2Q81G8N
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%