Found 39 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cathepsin K
(Homo sapiens (Human)) | BDBM50084655
(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O |r| Show InChI InChI=1S/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17-,18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137821
(((S)-5-tert-Butoxycarbonylamino-6-oxo-hexyl)-carba...)Show InChI InChI=1S/C13H24N2O5/c1-13(2,3)20-12(18)15-10(9-16)7-5-6-8-14-11(17)19-4/h9-10H,5-8H2,1-4H3,(H,14,17)(H,15,18)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137824
(((S)-1-Formyl-4-phenyl-butyl)-carbamic acid tert-b...)Show InChI InChI=1S/C16H23NO3/c1-16(2,3)20-15(19)17-14(12-18)11-7-10-13-8-5-4-6-9-13/h4-6,8-9,12,14H,7,10-11H2,1-3H3,(H,17,19)/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
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GoogleScholar
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| CHEMBL
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PC sid
UniChem
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137813
(((S)-4-Cyclohexyl-1-formyl-butyl)-carbamic acid te...)Show InChI InChI=1S/C16H29NO3/c1-16(2,3)20-15(19)17-14(12-18)11-7-10-13-8-5-4-6-9-13/h12-14H,4-11H2,1-3H3,(H,17,19)/t14-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
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| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137814
(((S)-1-Formyl-heptyl)-carbamic acid tert-butyl est...)Show InChI InChI=1S/C13H25NO3/c1-5-6-7-8-9-11(10-15)14-12(16)17-13(2,3)4/h10-11H,5-9H2,1-4H3,(H,14,16)/t11-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137816
(((S)-1-Cyclohexyl-2-oxo-ethyl)-carbamic acid tert-...)Show InChI InChI=1S/C13H23NO3/c1-13(2,3)17-12(16)14-11(9-15)10-7-5-4-6-8-10/h9-11H,4-8H2,1-3H3,(H,14,16)/t11-/m1/s1 | PDB
MMDB
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MMDB
PDB
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137797
(((S)-3-Cyclohexyl-1-formyl-propyl)-carbamic acid t...)Show InChI InChI=1S/C15H27NO3/c1-15(2,3)19-14(18)16-13(11-17)10-9-12-7-5-4-6-8-12/h11-13H,4-10H2,1-3H3,(H,16,18)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| CHEMBL
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| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137820
(CHEMBL92972 | {(S)-1-Formyl-4-[methyl-(2,2,2-trifl...)Show SMILES CN(CCC[C@H](NC(=O)OC(C)(C)C)C=O)C(=O)C(F)(F)F Show InChI InChI=1S/C13H21F3N2O4/c1-12(2,3)22-11(21)17-9(8-19)6-5-7-18(4)10(20)13(14,15)16/h8-9H,5-7H2,1-4H3,(H,17,21)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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GoogleScholar
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| CHEMBL
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| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137810
(((S)-1-Formyl-3-phenyl-propyl)-carbamic acid tert-...)Show InChI InChI=1S/C15H21NO3/c1-15(2,3)19-14(18)16-13(11-17)10-9-12-7-5-4-6-8-12/h4-8,11,13H,9-10H2,1-3H3,(H,16,18)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137822
(((S)-1-Formyl-3-methyl-butyl)-carbamic acid tert-b...)Show InChI InChI=1S/C11H21NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h7-9H,6H2,1-5H3,(H,12,14)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
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PC cid
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| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137805
(((S)-2-Cyclohexyl-1-formyl-ethyl)-carbamic acid te...)Show InChI InChI=1S/C14H25NO3/c1-14(2,3)18-13(17)15-12(10-16)9-11-7-5-4-6-8-11/h10-12H,4-9H2,1-3H3,(H,15,17)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
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PC cid
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| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137825
(((S)-1-Formyl-butyl)-carbamic acid tert-butyl este...)Show InChI InChI=1S/C10H19NO3/c1-5-6-8(7-12)11-9(13)14-10(2,3)4/h7-8H,5-6H2,1-4H3,(H,11,13)/t8-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
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| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137802
(((S)-2-Benzyloxy-1-formyl-ethyl)-carbamic acid ter...)Show InChI InChI=1S/C15H21NO4/c1-15(2,3)20-14(18)16-13(9-17)11-19-10-12-7-5-4-6-8-12/h4-9,13H,10-11H2,1-3H3,(H,16,18)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
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CHEMBL
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| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137803
(((R)-2-Benzylsulfanyl-1-formyl-ethyl)-carbamic aci...)Show InChI InChI=1S/C15H21NO3S/c1-15(2,3)19-14(18)16-13(9-17)11-20-10-12-7-5-4-6-8-12/h4-9,13H,10-11H2,1-3H3,(H,16,18)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
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DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
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| PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137812
(((S)-1-Formyl-pent-3-enyl)-carbamic acid tert-buty...)Show InChI InChI=1S/C11H19NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h5-6,8-9H,7H2,1-4H3,(H,12,14)/b6-5-/t9-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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PC cid
PC sid
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Similars
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| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137817
(CHEMBL92971 | [(S)-1-Formyl-5-(2,2,2-trifluoro-ace...)Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)C(F)(F)F)C=O Show InChI InChI=1S/C13H21F3N2O4/c1-12(2,3)22-11(21)18-9(8-19)6-4-5-7-17-10(20)13(14,15)16/h8-9H,4-7H2,1-3H3,(H,17,20)(H,18,21)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
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| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137791
(CHEMBL92465 | {(S)-1-Formyl-5-[methyl-(2,2,2-trifl...)Show SMILES CN(CCCC[C@H](NC(=O)OC(C)(C)C)C=O)C(=O)C(F)(F)F Show InChI InChI=1S/C14H23F3N2O4/c1-13(2,3)23-12(22)18-10(9-20)7-5-6-8-19(4)11(21)14(15,16)17/h9-10H,5-8H2,1-4H3,(H,18,22)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137790
(((S)-1-Formyl-pentyl)-carbamic acid tert-butyl est...)Show InChI InChI=1S/C11H21NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h8-9H,5-7H2,1-4H3,(H,12,14)/t9-/m0/s1 | PDB
MMDB
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| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137793
(((S)-2-Oxo-1-phenyl-ethyl)-carbamic acid tert-buty...)Show InChI InChI=1S/C13H17NO3/c1-13(2,3)17-12(16)14-11(9-15)10-7-5-4-6-8-10/h4-9,11H,1-3H3,(H,14,16)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137788
(((S)-1-Formyl-propyl)-carbamic acid tert-butyl est...)Show InChI InChI=1S/C9H17NO3/c1-5-7(6-11)10-8(12)13-9(2,3)4/h6-7H,5H2,1-4H3,(H,10,12)/t7-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137808
(((S)-1-Formyl-3-methylsulfanyl-propyl)-carbamic ac...)Show InChI InChI=1S/C10H19NO3S/c1-10(2,3)14-9(13)11-8(7-12)5-6-15-4/h7-8H,5-6H2,1-4H3,(H,11,13)/t8-/m0/s1 | PDB
MMDB
Reactome pathway
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CHEMBL
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| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137809
(((S)-1-Formyl-3-methyl-but-3-enyl)-carbamic acid t...)Show InChI InChI=1S/C11H19NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h7,9H,1,6H2,2-5H3,(H,12,14)/t9-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137806
(((R)-2-Ethylsulfanyl-1-formyl-ethyl)-carbamic acid...)Show InChI InChI=1S/C10H19NO3S/c1-5-15-7-8(6-12)11-9(13)14-10(2,3)4/h6,8H,5,7H2,1-4H3,(H,11,13)/t8-/m1/s1 | PDB
MMDB
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GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137811
(((S)-5,5,5-Trifluoro-1-formyl-pentyl)-carbamic aci...)Show InChI InChI=1S/C11H18F3NO3/c1-10(2,3)18-9(17)15-8(7-16)5-4-6-11(12,13)14/h7-8H,4-6H2,1-3H3,(H,15,17)/t8-/m0/s1 | PDB
MMDB
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GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137800
(CHEMBL92993 | {(S)-1-Formyl-3-[methyl-(2,2,2-trifl...)Show SMILES CN(CC[C@H](NC(=O)OC(C)(C)C)C=O)C(=O)C(F)(F)F Show InChI InChI=1S/C12H19F3N2O4/c1-11(2,3)21-10(20)16-8(7-18)5-6-17(4)9(19)12(13,14)15/h7-8H,5-6H2,1-4H3,(H,16,20)/t8-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137818
(((S)-1-Formyl-2-phenyl-ethyl)-carbamic acid tert-b...)Show InChI InChI=1S/C14H19NO3/c1-14(2,3)18-13(17)15-12(10-16)9-11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3,(H,15,17)/t12-/m0/s1 | PDB
MMDB
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| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137792
(((S)-1-Formyl-hexyl)-carbamic acid tert-butyl este...)Show InChI InChI=1S/C12H23NO3/c1-5-6-7-8-10(9-14)13-11(15)16-12(2,3)4/h9-10H,5-8H2,1-4H3,(H,13,15)/t10-/m0/s1 | PDB
MMDB
Reactome pathway
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UniChem
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| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137789
(((R)-1-Formyl-2-methyl-butyl)-carbamic acid tert-b...)Show InChI InChI=1S/C11H21NO3/c1-6-8(2)9(7-13)12-10(14)15-11(3,4)5/h7-9H,6H2,1-5H3,(H,12,14)/t8?,9-/m0/s1 | PDB
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| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137794
(((S)-1-Formyl-pent-3-enyl)-carbamic acid tert-buty...)Show InChI InChI=1S/C11H19NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h5-6,8-9H,7H2,1-4H3,(H,12,14)/b6-5+/t9-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137795
(((S)-1-Formyl-2-methyl-propyl)-carbamic acid tert-...)Show InChI InChI=1S/C10H19NO3/c1-7(2)8(6-12)11-9(13)14-10(3,4)5/h6-8H,1-5H3,(H,11,13)/t8-/m1/s1 | PDB
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| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137807
(((S)-1-Methyl-2-oxo-ethyl)-carbamic acid tert-buty...)Show InChI InChI=1S/C8H15NO3/c1-6(5-10)9-7(11)12-8(2,3)4/h5-6H,1-4H3,(H,9,11)/t6-/m0/s1 | PDB
MMDB
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GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137796
(((S)-1-Formyl-2-methyl-butyl)-carbamic acid tert-b...)Show InChI InChI=1S/C11H21NO3/c1-6-8(2)9(7-13)12-10(14)15-11(3,4)5/h7-9H,6H2,1-5H3,(H,12,14)/t8?,9-/m1/s1 | PDB
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| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137823
(((S)-1-Formyl-3,3-dimethyl-butyl)-carbamic acid te...)Show InChI InChI=1S/C12H23NO3/c1-11(2,3)7-9(8-14)13-10(15)16-12(4,5)6/h8-9H,7H2,1-6H3,(H,13,15)/t9-/m0/s1 | PDB
MMDB
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| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137815
(((S)-2-tert-Butoxycarbonylamino-3-oxo-propyl)-carb...)Show InChI InChI=1S/C10H18N2O5/c1-10(2,3)17-9(15)12-7(6-13)5-11-8(14)16-4/h6-7H,5H2,1-4H3,(H,11,14)(H,12,15)/t7-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137801
(((S)-1-Formyl-pent-3-ynyl)-carbamic acid tert-buty...)Show InChI InChI=1S/C11H17NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h8-9H,7H2,1-4H3,(H,12,14)/t9-/m0/s1 | PDB
MMDB
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| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137798
(((S)-2-Ethoxy-1-formyl-ethyl)-carbamic acid tert-b...)Show InChI InChI=1S/C10H19NO4/c1-5-14-7-8(6-12)11-9(13)15-10(2,3)4/h6,8H,5,7H2,1-4H3,(H,11,13)/t8-/m1/s1 | PDB
MMDB
Reactome pathway
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| PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137804
(((S)-1-Formyl-3-methoxy-propyl)-carbamic acid tert...)Show InChI InChI=1S/C10H19NO4/c1-10(2,3)15-9(13)11-8(7-12)5-6-14-4/h7-8H,5-6H2,1-4H3,(H,11,13)/t8-/m0/s1 | PDB
MMDB
Reactome pathway
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| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137819
((2-Oxo-ethyl)-carbamic acid tert-butyl ester | CHE...)Show InChI InChI=1S/C7H13NO3/c1-7(2,3)11-6(10)8-4-5-9/h5H,4H2,1-3H3,(H,8,10) | PDB
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| n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50137799
(((S)-1-Formyl-2,2-dimethyl-propyl)-carbamic acid t...)Show InChI InChI=1S/C11H21NO3/c1-10(2,3)8(7-13)12-9(14)15-11(4,5)6/h7-8H,1-6H3,(H,12,14)/t8-/m1/s1 | PDB
MMDB
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| n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibiory activity against recombinant human cathepsin K |
Bioorg Med Chem Lett 14: 275-8 (2003)
BindingDB Entry DOI: 10.7270/Q2GM86PN |
More data for this
Ligand-Target Pair | |
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