Affinity Data by PubMed id=1495016

PubMed code 1495016

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229848 (CHEMBL1202910) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H] clonidine as radioligand in rat brain cortex				J Med Chem 35: 2855-63 (1992) BindingDB Entry DOI: 10.7270/Q2F76FS1
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229848 (CHEMBL1202910) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H]- clonidine as radioligand in rat brain cortex.				J Med Chem 35: 2855-63 (1992) BindingDB Entry DOI: 10.7270/Q2F76FS1
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50229848 (CHEMBL1202910) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H]- clonidine as radioligand in rat brain cortex.				J Med Chem 35: 2855-63 (1992) BindingDB Entry DOI: 10.7270/Q2F76FS1
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%