Affinity Data by PubMed id=14998322

PubMed code 14998322

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Methionine aminopeptidase (Staphylococcus aureus)	BDBM17869 ((3S)-3-amino-1-(cyclopropylamino)heptane-2,2-diol ...) Show SMILES CCCC[C@H](N)C(=O)CNC1CC1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	7.5	22
Morphochem AG					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				J Med Chem 47: 1325-8 (2004) Article DOI: 10.1021/jm034188j BindingDB Entry DOI: 10.7270/Q2GX48TV
Morphochem AG					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase (Staphylococcus aureus)	BDBM17868 ((2S)-2-amino-4-(methylsulfanyl)-1-(pyridin-2-yl)bu...) Show SMILES CSCC[C@H](N)C(=O)c1ccccn1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.5	22
Morphochem AG					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				J Med Chem 47: 1325-8 (2004) Article DOI: 10.1021/jm034188j BindingDB Entry DOI: 10.7270/Q2GX48TV
Morphochem AG					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase (Staphylococcus aureus)	BDBM17867 ((2S)-2-amino-4-(methylsulfanyl)-1-(1,3-thiazol-2-y...) Show SMILES CSCC[C@H](N)C(=O)c1nccs1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	7.5	22
Morphochem AG					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				J Med Chem 47: 1325-8 (2004) Article DOI: 10.1021/jm034188j BindingDB Entry DOI: 10.7270/Q2GX48TV
Morphochem AG					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%