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PubMed code 15026066

Compile data set for download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142763
PNG
(CHEMBL50184 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCc1sc(CCc2cc(cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)N2CCOCC2)nc1C
Show InChI InChI=1S/C28H36ClN5O3S/c1-5-25-19(4)31-27(38-25)7-6-22-15-24(34-8-10-36-11-9-34)16-26(32-22)30-17-20-12-21(29)14-23(13-20)33-28(35)37-18(2)3/h12-16,18H,5-11,17H2,1-4H3,(H,30,32)(H,33,35)
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n/an/a 1.40n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142773
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCc1sc(CCc2cc(OC3CCOCC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C29H37ClN4O4S/c1-5-26-19(4)32-28(39-26)7-6-22-15-25(38-24-8-10-36-11-9-24)16-27(33-22)31-17-20-12-21(30)14-23(13-20)34-29(35)37-18(2)3/h12-16,18,24H,5-11,17H2,1-4H3,(H,31,33)(H,34,35)
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n/an/a 4.40n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50404353
PNG
(CHEMBL2113710)
Show SMILES CC\C=C/CCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C30H39ClN4O3S/c1-6-8-9-10-13-37-26-17-24(11-12-29-33-21(5)27(7-2)39-29)34-28(18-26)32-19-22-14-23(31)16-25(15-22)35-30(36)38-20(3)4/h8-9,14-18,20H,6-7,10-13,19H2,1-5H3,(H,32,34)(H,35,36)/b9-8-
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n/an/a 4.70n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142770
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCC(CC)Oc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C29H39ClN4O3S/c1-7-24(8-2)37-25-15-22(10-11-28-32-19(6)26(9-3)38-28)33-27(16-25)31-17-20-12-21(30)14-23(13-20)34-29(35)36-18(4)5/h12-16,18,24H,7-11,17H2,1-6H3,(H,31,33)(H,34,35)
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n/an/a 5.5n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142762
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCc1sc(CCc2cc(OCCCc3cccnc3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C32H38ClN5O3S/c1-5-29-22(4)36-31(42-29)11-10-26-17-28(40-13-7-9-23-8-6-12-34-19-23)18-30(37-26)35-20-24-14-25(33)16-27(15-24)38-32(39)41-21(2)3/h6,8,12,14-19,21H,5,7,9-11,13,20H2,1-4H3,(H,35,37)(H,38,39)
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n/an/a 6.5n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142761
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCc1sc(CCc2cc(OC(C)COC)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C28H37ClN4O4S/c1-7-25-19(5)31-27(38-25)9-8-22-13-24(37-18(4)16-35-6)14-26(32-22)30-15-20-10-21(29)12-23(11-20)33-28(34)36-17(2)3/h10-14,17-18H,7-9,15-16H2,1-6H3,(H,30,32)(H,33,34)
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n/an/a 8.40n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142769
PNG
(CHEMBL52282 | [3-Chloro-5-({4-cyclobutoxy-6-[2-(5-...)
Show SMILES CCc1sc(CCc2cc(OC3CCC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C28H35ClN4O3S/c1-5-25-18(4)31-27(37-25)10-9-21-14-24(36-23-7-6-8-23)15-26(32-21)30-16-19-11-20(29)13-22(12-19)33-28(34)35-17(2)3/h11-15,17,23H,5-10,16H2,1-4H3,(H,30,32)(H,33,34)
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n/an/a 11n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142782
PNG
(CHEMBL264820 | [3-Chloro-5-({4-cyclopentyloxy-6-[2...)
Show SMILES CCc1sc(CCc2cc(OC3CCCC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C29H37ClN4O3S/c1-5-26-19(4)32-28(38-26)11-10-22-15-25(37-24-8-6-7-9-24)16-27(33-22)31-17-20-12-21(30)14-23(13-20)34-29(35)36-18(2)3/h12-16,18,24H,5-11,17H2,1-4H3,(H,31,33)(H,34,35)
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n/an/a 11n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142775
PNG
(CHEMBL298983 | [3-Chloro-5-({6-[2-(5-ethyl-4-methy...)
Show SMILES CCc1sc(CCc2cc(OC(C)C)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C27H35ClN4O3S/c1-7-24-18(6)30-26(36-24)9-8-21-13-23(34-16(2)3)14-25(31-21)29-15-19-10-20(28)12-22(11-19)32-27(33)35-17(4)5/h10-14,16-17H,7-9,15H2,1-6H3,(H,29,31)(H,32,33)
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n/an/a 12n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142779
PNG
(CHEMBL48950 | [3-({4-Butoxy-6-[2-(5-ethyl-4-methyl...)
Show SMILES CCCCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C28H37ClN4O3S/c1-6-8-11-35-24-15-22(9-10-27-31-19(5)25(7-2)37-27)32-26(16-24)30-17-20-12-21(29)14-23(13-20)33-28(34)36-18(3)4/h12-16,18H,6-11,17H2,1-5H3,(H,30,32)(H,33,34)
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n/an/a 16n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142766
PNG
(CHEMBL299598 | [3-Chloro-5-({6-[2-(5-ethyl-4-methy...)
Show SMILES CCCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C27H35ClN4O3S/c1-6-10-34-23-14-21(8-9-26-30-18(5)24(7-2)36-26)31-25(15-23)29-16-19-11-20(28)13-22(12-19)32-27(33)35-17(3)4/h11-15,17H,6-10,16H2,1-5H3,(H,29,31)(H,32,33)
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n/an/a 17n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142771
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCc1sc(CCc2cc(OCC3(C)CC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C29H37ClN4O3S/c1-6-25-19(4)32-27(38-25)8-7-22-14-24(36-17-29(5)9-10-29)15-26(33-22)31-16-20-11-21(30)13-23(12-20)34-28(35)37-18(2)3/h11-15,18H,6-10,16-17H2,1-5H3,(H,31,33)(H,34,35)
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n/an/a 17n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142764
PNG
((3-Chloro-5-{[6-[2-(5-ethyl-4-methyl-thiazol-2-yl)...)
Show SMILES CCc1sc(CCc2cc(OCCCc3ccccc3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C33H39ClN4O3S/c1-5-30-23(4)36-32(42-30)14-13-27-19-29(40-15-9-12-24-10-7-6-8-11-24)20-31(37-27)35-21-25-16-26(34)18-28(17-25)38-33(39)41-22(2)3/h6-8,10-11,16-20,22H,5,9,12-15,21H2,1-4H3,(H,35,37)(H,38,39)
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n/an/a 20n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142777
PNG
(CHEMBL49461 | [3-Chloro-5-({4-cyclohexyloxy-6-[2-(...)
Show SMILES CCc1sc(CCc2cc(OC3CCCCC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C30H39ClN4O3S/c1-5-27-20(4)33-29(39-27)12-11-23-16-26(38-25-9-7-6-8-10-25)17-28(34-23)32-18-21-13-22(31)15-24(14-21)35-30(36)37-19(2)3/h13-17,19,25H,5-12,18H2,1-4H3,(H,32,34)(H,35,36)
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n/an/a 29n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142772
PNG
(CHEMBL48897 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCc1sc(CCc2cc(OCCc3ccccc3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C32H37ClN4O3S/c1-5-29-22(4)35-31(41-29)12-11-26-18-28(39-14-13-23-9-7-6-8-10-23)19-30(36-26)34-20-24-15-25(33)17-27(16-24)37-32(38)40-21(2)3/h6-10,15-19,21H,5,11-14,20H2,1-4H3,(H,34,36)(H,37,38)
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n/an/a 30n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142781
PNG
(CHEMBL48947 | [3-Chloro-5-({4-ethoxy-6-[2-(5-ethyl...)
Show SMILES CCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C26H33ClN4O3S/c1-6-23-17(5)29-25(35-23)9-8-20-13-22(33-7-2)14-24(30-20)28-15-18-10-19(27)12-21(11-18)31-26(32)34-16(3)4/h10-14,16H,6-9,15H2,1-5H3,(H,28,30)(H,31,32)
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n/an/a 33n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142774
PNG
(CHEMBL48456 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCCCCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C29H39ClN4O3S/c1-6-8-9-12-36-25-16-23(10-11-28-32-20(5)26(7-2)38-28)33-27(17-25)31-18-21-13-22(30)15-24(14-21)34-29(35)37-19(3)4/h13-17,19H,6-12,18H2,1-5H3,(H,31,33)(H,34,35)
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n/an/a 35n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142768
PNG
(CHEMBL422583 | [3-Chloro-5-({4-(2,2-dimethyl-propo...)
Show SMILES CCc1sc(CCc2cc(OCC(C)(C)C)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C29H39ClN4O3S/c1-8-25-19(4)32-27(38-25)10-9-22-14-24(36-17-29(5,6)7)15-26(33-22)31-16-20-11-21(30)13-23(12-20)34-28(35)37-18(2)3/h11-15,18H,8-10,16-17H2,1-7H3,(H,31,33)(H,34,35)
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n/an/a 55n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142765
PNG
(CHEMBL51422 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCCCCCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C30H41ClN4O3S/c1-6-8-9-10-13-37-26-17-24(11-12-29-33-21(5)27(7-2)39-29)34-28(18-26)32-19-22-14-23(31)16-25(15-22)35-30(36)38-20(3)4/h14-18,20H,6-13,19H2,1-5H3,(H,32,34)(H,35,36)
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n/an/a 63n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142780
PNG
(CHEMBL48493 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCCCCCCOc1cc(CCc2nc(C)c(CC)s2)nc(NCc2cc(Cl)cc(NC(=O)OC(C)C)c2)c1
Show InChI InChI=1S/C31H43ClN4O3S/c1-6-8-9-10-11-14-38-27-18-25(12-13-30-34-22(5)28(7-2)40-30)35-29(19-27)33-20-23-15-24(32)17-26(16-23)36-31(37)39-21(3)4/h15-19,21H,6-14,20H2,1-5H3,(H,33,35)(H,36,37)
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n/an/a 72n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142778
PNG
(CHEMBL49795 | [3-Chloro-5-({6-[2-(5-ethyl-4-methyl...)
Show SMILES CCc1sc(CCc2cc(OC)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C25H31ClN4O3S/c1-6-22-16(4)28-24(34-22)8-7-19-12-21(32-5)13-23(29-19)27-14-17-9-18(26)11-20(10-17)30-25(31)33-15(2)3/h9-13,15H,6-8,14H2,1-5H3,(H,27,29)(H,30,31)
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n/an/a 234n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50142767
PNG
(CHEMBL45869 | [3-({4-Benzyloxy-6-[2-(5-ethyl-4-met...)
Show SMILES CCc1sc(CCc2cc(OCc3ccccc3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C
Show InChI InChI=1S/C31H35ClN4O3S/c1-5-28-21(4)34-30(40-28)12-11-25-16-27(38-19-22-9-7-6-8-10-22)17-29(35-25)33-18-23-13-24(32)15-26(14-23)36-31(37)39-20(2)3/h6-10,13-17,20H,5,11-12,18-19H2,1-4H3,(H,33,35)(H,36,37)
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n/an/a 237n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human recombinant NPY Y1 receptor in CHO/dhFr- cell membranes using [125I]-PYY

Bioorg Med Chem Lett 14: 1761-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.049
BindingDB Entry DOI: 10.7270/Q26D5SFV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%