Found 34 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147132
(2,2,2-Trifluoro-ethanesulfonic acid [3-(2-methyl-b...)Show SMILES CCC(C)COc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C19H23F3N2O3S/c1-3-15(2)13-27-18-8-4-7-17(10-18)24(12-16-6-5-9-23-11-16)28(25,26)14-19(20,21)22/h4-11,15H,3,12-14H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147156
(2,2,2-Trifluoro-ethanesulfonic acid (3-cyclopentyl...)Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC2CCCC2)c1 Show InChI InChI=1S/C19H21F3N2O3S/c20-19(21,22)14-28(25,26)24(13-15-5-4-10-23-12-15)16-6-3-9-18(11-16)27-17-7-1-2-8-17/h3-6,9-12,17H,1-2,7-8,13-14H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147147
(CHEMBL104541 | Ethanesulfonic acid (4-benzyl-pheny...)Show InChI InChI=1S/C21H22N2O2S/c1-2-26(24,25)23(17-20-9-6-14-22-16-20)21-12-10-19(11-13-21)15-18-7-4-3-5-8-18/h3-14,16H,2,15,17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147128
(CHEMBL104129 | Ethanesulfonic acid [3-(hydroxy-phe...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(c1)C(O)c1ccccc1 Show InChI InChI=1S/C21H22N2O3S/c1-2-27(25,26)23(16-17-8-7-13-22-15-17)20-12-6-11-19(14-20)21(24)18-9-4-3-5-10-18/h3-15,21,24H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147133
(CHEMBL106909 | Ethanesulfonic acid (3-benzyloxy-ph...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C21H22N2O3S/c1-2-27(24,25)23(16-19-10-7-13-22-15-19)20-11-6-12-21(14-20)26-17-18-8-4-3-5-9-18/h3-15H,2,16-17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 440 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147137
(2,2,2-Trifluoro-ethanesulfonic acid (3-sec-butoxy-...)Show SMILES CCC(C)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C18H21F3N2O3S/c1-3-14(2)26-17-8-4-7-16(10-17)23(12-15-6-5-9-22-11-15)27(24,25)13-18(19,20)21/h4-11,14H,3,12-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147144
(CHEMBL319612 | Ethanesulfonic acid [4-(hydroxy-phe...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(cc1)C(O)c1ccccc1 Show InChI InChI=1S/C21H22N2O3S/c1-2-27(25,26)23(16-17-7-6-14-22-15-17)20-12-10-19(11-13-20)21(24)18-8-4-3-5-9-18/h3-15,21,24H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147152
(CHEMBL323080 | Ethanesulfonic acid (4-phenoxymethy...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(COc2ccccc2)cc1 Show InChI InChI=1S/C21H22N2O3S/c1-2-27(24,25)23(16-19-7-6-14-22-15-19)20-12-10-18(11-13-20)17-26-21-8-4-3-5-9-21/h3-15H,2,16-17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147157
(2,2,2-Trifluoro-ethanesulfonic acid (3-benzyloxy-p...)Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C21H19F3N2O3S/c22-21(23,24)16-30(27,28)26(14-18-8-5-11-25-13-18)19-9-4-10-20(12-19)29-15-17-6-2-1-3-7-17/h1-13H,14-16H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147154
(2,2,2-Trifluoro-ethanesulfonic acid (3-cyclohexylo...)Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC2CCCCC2)c1 Show InChI InChI=1S/C20H23F3N2O3S/c21-20(22,23)15-29(26,27)25(14-16-6-5-11-24-13-16)17-7-4-10-19(12-17)28-18-8-2-1-3-9-18/h4-7,10-13,18H,1-3,8-9,14-15H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147129
(CHEMBL106774 | Ethanesulfonic acid [4-(fluoro-phen...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(cc1)C(F)c1ccccc1 Show InChI InChI=1S/C21H21FN2O2S/c1-2-27(25,26)24(16-17-7-6-14-23-15-17)20-12-10-19(11-13-20)21(22)18-8-4-3-5-9-18/h3-15,21H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147130
(2,2,2-Trifluoro-ethanesulfonic acid pyridin-3-ylme...)Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C15H12F6N2O3S/c16-14(17,18)10-27(24,25)23(9-11-3-2-6-22-8-11)12-4-1-5-13(7-12)26-15(19,20)21/h1-8H,9-10H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147145
(CHEMBL320151 | Ethanesulfonic acid [3-(fluoro-phen...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(c1)C(F)c1ccccc1 Show InChI InChI=1S/C21H21FN2O2S/c1-2-27(25,26)24(16-17-8-7-13-23-15-17)20-12-6-11-19(14-20)21(22)18-9-4-3-5-10-18/h3-15,21H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147149
(CHEMBL421406 | Ethanesulfonic acid (3-phenoxy-phen...)Show InChI InChI=1S/C20H20N2O3S/c1-2-26(23,24)22(16-17-8-7-13-21-15-17)18-9-6-12-20(14-18)25-19-10-4-3-5-11-19/h3-15H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147146
(CHEMBL440328 | {3-[Pyridin-3-ylmethyl-(trifluoro-e...)Show SMILES CCOC(=O)COc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C18H19F3N2O5S/c1-2-27-17(24)12-28-16-7-3-6-15(9-16)23(11-14-5-4-8-22-10-14)29(25,26)13-18(19,20)21/h3-10H,2,11-13H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 640 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147148
(CHEMBL318309 | Ethanesulfonic acid [3-(1-phenyl-vi...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(c1)C(=C)c1ccccc1 Show InChI InChI=1S/C22H22N2O2S/c1-3-27(25,26)24(17-19-9-8-14-23-16-19)22-13-7-12-21(15-22)18(2)20-10-5-4-6-11-20/h4-16H,2-3,17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147155
(2,2,2-Trifluoro-ethanesulfonic acid pyridin-3-ylme...)Show SMILES FC(F)(F)COc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C16H14F6N2O3S/c17-15(18,19)10-27-14-5-1-4-13(7-14)24(9-12-3-2-6-23-8-12)28(25,26)11-16(20,21)22/h1-8H,9-11H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147134
(2,2,2-Trifluoro-ethanesulfonic acid (3-methoxy-phe...)Show InChI InChI=1S/C15H15F3N2O3S/c1-23-14-6-2-5-13(8-14)20(10-12-4-3-7-19-9-12)24(21,22)11-15(16,17)18/h2-9H,10-11H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147136
(CHEMBL323138 | Ethanesulfonic acid [4-(1-phenyl-et...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(cc1)C(C)c1ccccc1 Show InChI InChI=1S/C22H24N2O2S/c1-3-27(25,26)24(17-19-8-7-15-23-16-19)22-13-11-21(12-14-22)18(2)20-9-5-4-6-10-20/h4-16,18H,3,17H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147140
(CHEMBL104140 | Ethanesulfonic acid [4-(1-phenyl-vi...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(cc1)C(=C)c1ccccc1 Show InChI InChI=1S/C22H22N2O2S/c1-3-27(25,26)24(17-19-8-7-15-23-16-19)22-13-11-21(12-14-22)18(2)20-9-5-4-6-10-20/h4-16H,2-3,17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 780 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147150
(2,2,2-Trifluoro-ethanesulfonic acid (3-cyclobutoxy...)Show SMILES FC(F)(F)CS(=O)(=O)N(Cc1cccnc1)c1cccc(OC2CCC2)c1 Show InChI InChI=1S/C18H19F3N2O3S/c19-18(20,21)13-27(24,25)23(12-14-4-3-9-22-11-14)15-5-1-8-17(10-15)26-16-6-2-7-16/h1,3-5,8-11,16H,2,6-7,12-13H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147135
(CHEMBL104191 | Ethanesulfonic acid (3-phenoxymethy...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(COc2ccccc2)c1 Show InChI InChI=1S/C21H22N2O3S/c1-2-27(24,25)23(16-19-9-7-13-22-15-19)20-10-6-8-18(14-20)17-26-21-11-4-3-5-12-21/h3-15H,2,16-17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147138
(CHEMBL104818 | Ethanesulfonic acid (3-benzyl-pheny...)Show InChI InChI=1S/C21H22N2O2S/c1-2-26(24,25)23(17-20-11-7-13-22-16-20)21-12-6-10-19(15-21)14-18-8-4-3-5-9-18/h3-13,15-16H,2,14,17H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147139
(2,2,2-Trifluoro-ethanesulfonic acid (3-isobutoxy-p...)Show SMILES CC(C)COc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C18H21F3N2O3S/c1-14(2)12-26-17-7-3-6-16(9-17)23(11-15-5-4-8-22-10-15)27(24,25)13-18(19,20)21/h3-10,14H,11-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147151
(2-Methyl-2-{3-[pyridin-3-ylmethyl-(2,2,2-trifluoro...)Show SMILES CCOC(=O)C(C)(C)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C20H23F3N2O5S/c1-4-29-18(26)19(2,3)30-17-9-5-8-16(11-17)25(13-15-7-6-10-24-12-15)31(27,28)14-20(21,22)23/h5-12H,4,13-14H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 88 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147153
(2-{3-[Pyridin-3-ylmethyl-(2,2,2-trifluoro-ethanesu...)Show SMILES CCOC(=O)C(C)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C19H21F3N2O5S/c1-3-28-18(25)14(2)29-17-8-4-7-16(10-17)24(12-15-6-5-9-23-11-15)30(26,27)13-19(20,21)22/h4-11,14H,3,12-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147125
(2,2,2-Trifluoro-ethanesulfonic acid (3-isopropoxy-...)Show SMILES CC(C)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C17H19F3N2O3S/c1-13(2)25-16-7-3-6-15(9-16)22(11-14-5-4-8-21-10-14)26(23,24)12-17(18,19)20/h3-10,13H,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147126
(2,2,2-Trifluoro-ethanesulfonic acid [3-(1-ethyl-pr...)Show SMILES CCC(CC)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C19H23F3N2O3S/c1-3-17(4-2)27-18-9-5-8-16(11-18)24(13-15-7-6-10-23-12-15)28(25,26)14-19(20,21)22/h5-12,17H,3-4,13-14H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147131
(CHEMBL104248 | Ethanesulfonic acid (3-benzoyl-phen...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-2-27(25,26)23(16-17-8-7-13-22-15-17)20-12-6-11-19(14-20)21(24)18-9-4-3-5-10-18/h3-15H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50130609
(CHEMBL104296 | Ethanesulfonic acid (4-phenoxy-phen...)Show InChI InChI=1S/C20H20N2O3S/c1-2-26(23,24)22(16-17-7-6-14-21-15-17)18-10-12-20(13-11-18)25-19-8-4-3-5-9-19/h3-15H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147143
(2,2,2-Trifluoro-ethanesulfonic acid [3-(1-methyl-b...)Show SMILES CCCC(C)Oc1cccc(c1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F Show InChI InChI=1S/C19H23F3N2O3S/c1-3-6-15(2)27-18-9-4-8-17(11-18)24(13-16-7-5-10-23-12-16)28(25,26)14-19(20,21)22/h4-5,7-12,15H,3,6,13-14H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147127
(CHEMBL107806 | Ethanesulfonic acid (4-benzoyl-phen...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1ccc(cc1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-2-27(25,26)23(16-17-7-6-14-22-15-17)20-12-10-19(11-13-20)21(24)18-8-4-3-5-9-18/h3-15H,2,16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147142
(CHEMBL105065 | Ethanesulfonic acid [3-(1-phenyl-et...)Show SMILES CCS(=O)(=O)N(Cc1cccnc1)c1cccc(c1)C(C)c1ccccc1 Show InChI InChI=1S/C22H24N2O2S/c1-3-27(25,26)24(17-19-9-8-14-23-16-19)22-13-7-12-21(15-22)18(2)20-10-5-4-6-11-20/h4-16,18H,3,17H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50147141
(CHEMBL104785 | Ethanesulfonic acid pyridin-3-ylmet...)Show InChI InChI=1S/C15H15F3N2O3S/c1-2-24(21,22)20(11-12-5-4-8-19-10-12)13-6-3-7-14(9-13)23-15(16,17)18/h3-10H,2,11H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Effective concentration against metabotropic glutamate receptor 2 |
Bioorg Med Chem Lett 14: 3099-102 (2004)
Article DOI: 10.1016/j.bmcl.2004.04.017
BindingDB Entry DOI: 10.7270/Q2222T69 |
More data for this
Ligand-Target Pair | |
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