BindingDB logo
myBDB logout

PubMed code 15217290

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50242053
PNG
(6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...)
Show SMILES CCCCCCCC\C=C/c1c2CCC[n+]2c(C)c(\C=C/CCCCCCCC)c1C
Show InChI InChI=1S/C30H50N/c1-5-7-9-11-13-15-17-19-22-28-26(3)29(30-24-21-25-31(30)27(28)4)23-20-18-16-14-12-10-8-6-2/h19-20,22-23H,5-18,21,24-25H2,1-4H3/q+1/b22-19-,23-20-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cells

J Nat Prod 67: 1036-8 (2004)


Article DOI: 10.1021/np049974l
BindingDB Entry DOI: 10.7270/Q29Z94P3
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50242056
PNG
(CHEMBL469856 | fuscinarin)
Show SMILES CC1OC(=O)c2c1c(O)c(O)c1OC(C)(C)CCc21
Show InChI InChI=1S/C14H16O5/c1-6-8-9(13(17)18-6)7-4-5-14(2,3)19-12(7)11(16)10(8)15/h6,15-16H,4-5H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of MIP1alpha binding to human CCR5 receptor

J Nat Prod 67: 1036-8 (2004)


Article DOI: 10.1021/np049974l
BindingDB Entry DOI: 10.7270/Q29Z94P3
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50242054
PNG
(CHEMBL469855 | ophiobolin C)
Show SMILES [#6]-[#6@@H](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@H]-1-[#6]-[#6][C@]2([#6])[#6]-[#6@H]3-[#6@H](-[#6](=O)-[#6][C@@]3([#6])[#8])\[#6](-[#6]=O)=[#6]/[#6]-[#6@@H]-12 |r,c:25|
Show InChI InChI=1S/C25H38O3/c1-16(2)7-6-8-17(3)19-11-12-24(4)13-21-23(22(27)14-25(21,5)28)18(15-26)9-10-20(19)24/h7,9,15,17,19-21,23,28H,6,8,10-14H2,1-5H3/b18-9-/t17-,19+,20-,21-,23+,24+,25+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cells

J Nat Prod 67: 1036-8 (2004)


Article DOI: 10.1021/np049974l
BindingDB Entry DOI: 10.7270/Q29Z94P3
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50242055
PNG
(19,20-epoxycytochalasin Q | CHEMBL449278)
Show SMILES C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]22[C@@H](\C=C\C[C@H](C)C(=O)[C@](C)(O)[C@@H]3O[C@H]3[C@H]2OC(C)=O)[C@@H]2O[C@]12C |r,t:18|
Show InChI InChI=1S/C30H37NO7/c1-15-10-9-13-19-24-29(5,38-24)16(2)21-20(14-18-11-7-6-8-12-18)31-27(34)30(19,21)26(36-17(3)32)22-25(37-22)28(4,35)23(15)33/h6-9,11-13,15-16,19-22,24-26,35H,10,14H2,1-5H3,(H,31,34)/b13-9+/t15-,16-,19-,20-,21-,22+,24-,25+,26+,28-,29+,30-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cells

J Nat Prod 67: 1036-8 (2004)


Article DOI: 10.1021/np049974l
BindingDB Entry DOI: 10.7270/Q29Z94P3
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%