Affinity Data by PubMed id=15317466

PubMed code 15317466

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50151412 ((R)-2-[(S)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(R)-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50117091 ((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-6,10,13-tr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151417 (4-((4R,5S,9R,14R)-7-Hydroxy-3-(R)-hydroxy-10,13-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151420 ((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-10,13-dime...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151424 ((1R,3R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151414 ((R)-4-((3R,6R,7S,10R,13R)-6-Fluoro-3,7-dihydroxy-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151415 ((3S,5R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151416 (CHEMBL424989 \| [(R)-3-((3R,7R,10S,13R)-3,7-Dihydro...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM21674 ((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	8.66E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bile acid receptor (Homo sapiens (Human))	BDBM50375577 (CHEMBL270311) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151411 ((R)-2-[(R)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(S)-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151413 ((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-6,10,13-tr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151418 ((R)-4-((3R,6R,7S,10R,13R)-3,6,7-Trihydroxy-10,13-d...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151427 ((R)-4-((3R,6R,7R,10S,13R)-6-Allyl-3,7-dihydroxy-10...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151431 ((R)-2-[(S)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(S)-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151419 ((3R,7R,10S,13R)-17-((R)-3-Amino-1-methyl-propyl)-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.68E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151422 ((R)-4-((3R,6S,7S,10R,13R)-6-Fluoro-3,7-dihydroxy-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151410 (CHEMBL189237 \| Sulfuric acid mono-[(R)-4-((3R,7R,1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.99E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151409 ((R)-2-[(R)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(R)-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151421 (3-((E)-2-{4-[3-(2,6-Dichloro-phenyl)-5-isopropyl-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151425 ((R)-4-[(3R,6R,7R,10S,13R)-3,7-Dihydroxy-6-(2-hydro...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.12E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM21675 ((4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bile acid receptor (Homo sapiens (Human))	BDBM50151423 (2-((4R,5S,9R,14S)-7-Hydroxy-3-(S)-hydroxy-10,13-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151428 (2-[(R)-3-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dime...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151430 ((R)-4-((3R,6R,7S,10R,13R)-3,7-Dihydroxy-6-methoxy-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Bile acid receptor (Homo sapiens (Human))	BDBM50151429 ((1S,3R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity for human Farnesoid X receptor in FRET assay				J Med Chem 47: 4559-69 (2004) Article DOI: 10.1021/jm049904b BindingDB Entry DOI: 10.7270/Q2JM2BD2
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%