BindingDB logo
myBDB logout

PubMed code 15324887

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase 1


(Homo sapiens (Human))
BDBM50151701
PNG
((S)-2-[3-(3,4-Dihydroxy-phenyl)-propionylamino]-su...)
Show SMILES Oc1ccc(CCC(=O)N[C@@H](CC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1O
Show InChI InChI=1S/C27H27NO7/c29-23-13-11-19(15-24(23)30)12-14-25(31)28-22(27(33)35-18-21-9-5-2-6-10-21)16-26(32)34-17-20-7-3-1-4-8-20/h1-11,13,15,22,29-30H,12,14,16-18H2,(H,28,31)/t22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL


Assay Description
Inhibitory activity against human Acyl-CoA:cholesterol acyltransferase-1


Bioorg Med Chem Lett 14: 4677-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.101
BindingDB Entry DOI: 10.7270/Q2K93701
More data for this
Ligand-Target Pair
Sterol O-acyltransferase 2


(Homo sapiens (Human))
BDBM50151701
PNG
((S)-2-[3-(3,4-Dihydroxy-phenyl)-propionylamino]-su...)
Show SMILES Oc1ccc(CCC(=O)N[C@@H](CC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1O
Show InChI InChI=1S/C27H27NO7/c29-23-13-11-19(15-24(23)30)12-14-25(31)28-22(27(33)35-18-21-9-5-2-6-10-21)16-26(32)34-17-20-7-3-1-4-8-20/h1-11,13,15,22,29-30H,12,14,16-18H2,(H,28,31)/t22-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.50E+4n/an/an/an/an/an/a



National Research Laboratory of Lipid Metabolism and Atherosclerosis

Curated by ChEMBL


Assay Description
Inhibitory activity against human Acyl-CoA:cholesterol acyltransferase-2


Bioorg Med Chem Lett 14: 4677-81 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.101
BindingDB Entry DOI: 10.7270/Q2K93701
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%