Affinity Data by PubMed id=15380230

PubMed code 15380230

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50118965 (4-Imidazol-1-yl-2-phenyl-chroman-7-ol \| CHEMBL9591...) Show SMILES Oc1ccc2C(CC(Oc2c1)c1ccccc1)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Biomolécules et Cibles Cellulaires Tumorales Curated by ChEMBL					Assay Description In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomes				Bioorg Med Chem Lett 14: 5215-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.090 BindingDB Entry DOI: 10.7270/Q26Q1WQ8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50118966 (1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole \|...) Show SMILES COc1ccc2C(CC(Oc2c1)c1ccccc1)n1ccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Biomolécules et Cibles Cellulaires Tumorales Curated by ChEMBL					Assay Description In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomes				Bioorg Med Chem Lett 14: 5215-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.090 BindingDB Entry DOI: 10.7270/Q26Q1WQ8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50153525 (2-Phenyl-4-[1,2,4]triazol-1-yl-chroman-7-ol \| CHEM...) Show SMILES Oc1ccc2C(CC(Oc2c1)c1ccccc1)n1cncn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Biomolécules et Cibles Cellulaires Tumorales Curated by ChEMBL					Assay Description In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomes				Bioorg Med Chem Lett 14: 5215-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.090 BindingDB Entry DOI: 10.7270/Q26Q1WQ8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50153523 (1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-[1,2,4]tria...) Show SMILES COc1ccc2C(CC(Oc2c1)c1ccccc1)n1cncn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Biomolécules et Cibles Cellulaires Tumorales Curated by ChEMBL					Assay Description In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomes				Bioorg Med Chem Lett 14: 5215-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.090 BindingDB Entry DOI: 10.7270/Q26Q1WQ8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50153524 (4-(7-Methoxy-2-phenyl-chroman-4-yl)-4H-[1,2,4]tria...) Show SMILES COc1ccc2C(CC(Oc2c1)c1ccccc1)n1cnnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
UPRES EA 1085 Biomolécules et Cibles Cellulaires Tumorales Curated by ChEMBL					Assay Description In vitro inhibition of [1,2,6,7-3H]androstenedione binding to Aromatase of human placental microsomes				Bioorg Med Chem Lett 14: 5215-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.090 BindingDB Entry DOI: 10.7270/Q26Q1WQ8
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%