Affinity Data by PubMed id=16002287

PubMed code 16002287

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT7R expressed in HEK-293 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT7R expressed in HEK-293 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50170157 (1-(2-Methoxy-phenyl)-4-[1-(2-trifluoromethyl-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT7R expressed in HEK-293 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
Université de Caen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%