Affinity Data by PubMed id=16190777

PubMed code 16190777

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50174673 (4-[1,2-bis(4-hydroxyphenyl)-1H-imidazol-4-yl]-3-ch...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-1 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50174671 (3-chloro-4-[2-(2-chloro-4-hydroxyphenyl)-1-(4-hydr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-1 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50174671 (3-chloro-4-[2-(2-chloro-4-hydroxyphenyl)-1-(4-hydr...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-2 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50174673 (4-[1,2-bis(4-hydroxyphenyl)-1H-imidazol-4-yl]-3-ch...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-2 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50174674 (4-[1,2-bis(4-hydroxyphenyl)-1H-imidazol-4-yl]pheno...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-1 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50174672 (4-[5-ethyl-1,2-bis(4-hydroxyphenyl)-1H-imidazol-4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Free University of Berlin Curated by ChEMBL					Assay Description Inhibitory concentration against human cyclooxygenase-1 evaluated by enzyme linked immunosorbent assay				J Med Chem 48: 6516-21 (2005) Article DOI: 10.1021/jm050190u BindingDB Entry DOI: 10.7270/Q21N80PG
Free University of Berlin Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%