Affinity Data by PubMed id=16236496

PubMed code 16236496

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16094 (2-[(4-phenylbenzene)amido]benzoic acid \| 2-[(biphe...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	700	-35.1	5.00E+3	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16096 (2-[(6-bromonaphthalene-2-)amido]benzoic acid \| 2-{...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc2cc(Br)ccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	-34.0	8.40E+3	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16098 (2-(naphthalene-2-amido)benzoic acid \| 2-[(naphthal...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	-32.8	1.38E+4	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16093 (2-[(biphenyl-4-ylcarbonyl)(methyl)amino]benzoic ac...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	-30.3	4.26E+4	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16095 (2-[(6-bromonaphthalene-2-)(methyl)amido]benzoic ac...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.08E+4	-28.3	9.34E+4	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16096 (2-[(6-bromonaphthalene-2-)amido]benzoic acid \| 2-{...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc2cc(Br)ccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.64E+4	-27.3	1.43E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16094 (2-[(4-phenylbenzene)amido]benzoic acid \| 2-[(biphe...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(cc1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	1.77E+4	-27.1	1.54E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16093 (2-[(biphenyl-4-ylcarbonyl)(methyl)amino]benzoic ac...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16098 (2-(naphthalene-2-amido)benzoic acid \| 2-[(naphthal...) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM16097 (2-[methyl(naphthalen-2-ylcarbonyl)amino]benzoic ac...) Show SMILES CN(C(=O)c1ccc2ccccc2c1)c1ccccc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16095 (2-[(6-bromonaphthalene-2-)(methyl)amido]benzoic ac...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM16097 (2-[methyl(naphthalen-2-ylcarbonyl)amino]benzoic ac...) Show SMILES CN(C(=O)c1ccc2ccccc2c1)c1ccccc1C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	8.0	25
University of Leeds					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 88-92 (2006) Article DOI: 10.1016/j.bmcl.2005.09.045 BindingDB Entry DOI: 10.7270/Q2N29V6N
University of Leeds					More data for this Ligand-Target Pair

* indicates data uncertainty>20%