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PubMed code 16263276

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50176345
PNG
((S)-2-(4-chloro-benzyl)-1,1,1-trifluoro-4-(5-fluor...)
Show SMILES COc1ccc(F)cc1C(C)(C)C[C@@](O)(Cc1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C20H21ClF4O2/c1-18(2,16-10-15(22)8-9-17(16)27-3)12-19(26,20(23,24)25)11-13-4-6-14(21)7-5-13/h4-10,26H,11-12H2,1-3H3/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 99n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to glucocorticoid receptor by Fluorescence polarization


Bioorg Med Chem Lett 16: 654-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.039
BindingDB Entry DOI: 10.7270/Q2BP02CC
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50176346
PNG
((R)-2-(4-chloro-benzyl)-1,1,1-trifluoro-4-(5-fluor...)
Show SMILES COc1ccc(F)cc1C(C)(C)C[C@](O)(Cc1ccc(Cl)cc1)C(F)(F)F
Show InChI InChI=1S/C20H21ClF4O2/c1-18(2,16-10-15(22)8-9-17(16)27-3)12-19(26,20(23,24)25)11-13-4-6-14(21)7-5-13/h4-10,26H,11-12H2,1-3H3/t19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity to glucocorticoid receptor by Fluorescence polarization


Bioorg Med Chem Lett 16: 654-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.039
BindingDB Entry DOI: 10.7270/Q2BP02CC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%