Affinity Data by PubMed id=16420039

PubMed code 16420039

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50180758 (4-((pyridin-4-ylthio)methyl)benzene-1,2-diol \| CHE...) Show SMILES Oc1ccc(CSc2ccncc2)cc1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology (AIST) Curated by ChEMBL					Assay Description Inhibition of MIF				J Med Chem 49: 523-33 (2006) Article DOI: 10.1021/jm050480a BindingDB Entry DOI: 10.7270/Q2HD7V63
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM31729 (8-bromanyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]qu...) Show SMILES OC(=O)C1Nc2ccc(Br)cc2C2C=CCC12 \|c:14\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology (AIST) Curated by ChEMBL					Assay Description Inhibition of MIF				J Med Chem 49: 523-33 (2006) Article DOI: 10.1021/jm050480a BindingDB Entry DOI: 10.7270/Q2HD7V63
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50180759 (5-isobutyramido-6-(2-(naphthalen-1-yl)ethyl)-3-(th...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology (AIST) Curated by ChEMBL					Assay Description Inhibition of MIF				J Med Chem 49: 523-33 (2006) Article DOI: 10.1021/jm050480a BindingDB Entry DOI: 10.7270/Q2HD7V63
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50180756 (3,3,3-tris(4-chlorophenyl)propanoic acid \| CHEMBL2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology (AIST) Curated by ChEMBL					Assay Description Inhibition of MIF				J Med Chem 49: 523-33 (2006) Article DOI: 10.1021/jm050480a BindingDB Entry DOI: 10.7270/Q2HD7V63
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50180757 ((4-benzylpiperazin-1-yl)(2-(3-cyclohexylpropyl)oxa...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology (AIST) Curated by ChEMBL					Assay Description Inhibition of MIF				J Med Chem 49: 523-33 (2006) Article DOI: 10.1021/jm050480a BindingDB Entry DOI: 10.7270/Q2HD7V63
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%