Affinity Data by PubMed id=16464575

PubMed code 16464575

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182218 (CHEMBL382875 \| [methyl-(7-nitro-benzo[1,2,5]oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182213 ((7-dimethylamino-2-oxo-2H-chromen-4-yl)-acetic aci...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182215 (CHEMBL205591 \| [methyl-(7-nitro-benzo[1,2,5]oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182219 ((7-dimethylamino-2-oxo-2H-chromen-4-yl)-acetic aci...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.1	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182214 (CHEMBL381040 \| [methyl-(7-nitro-benzo[1,2,5]oxadia...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50182217 ((7-dimethylamino-2-oxo-2H-chromen-4-yl)-acetic aci...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	695	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York-ESF Curated by ChEMBL					Assay Description Inhibition of PI3 kinase p110alpha/p85alpha complex				Bioorg Med Chem Lett 16: 2518-21 (2006) Article DOI: 10.1016/j.bmcl.2006.01.091 BindingDB Entry DOI: 10.7270/Q2XD119Z
State University of New York-ESF Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%