Affinity Data by PubMed id=16483773

PubMed code 16483773

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182922 (1-(benzyloxy)-3-(3-(pyridin-4-yl)-1H-indol-6-yl)ur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182920 (1-methyl-1-phenyl-3-(3-(pyridin-4-yl)-1H-indol-6-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182927 (1-methyl-3-(2-methyl-3-(pyridin-4-yl)-1H-indol-6-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182935 (CHEMBL379524 \| N-(2-methyl-3-(pyridin-4-yl)-1H-ind...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182925 (CHEMBL380132 \| N-(3-(pyridin-4-yl)-1H-indol-6-yl)b...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	364	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182921 (6-phenyl-3-(pyridin-4-yl)-1H-indole \| CHEMBL207621) Show SMILES c1[nH]c2cc(ccc2c1-c1ccncc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	456	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182919 (CHEMBL208261 \| ethyl 3-(pyridin-4-yl)-1H-indole-6-...) Show SMILES CCOC(=O)c1ccc2c(c[nH]c2c1)-c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	586	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50133727 (1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea \|...) Show SMILES Cn1cc(C#N)c2ccc(NC(=O)Nc3ccccc3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	722	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182931 (1-methoxy-3-(3-(pyridin-4-yl)-1H-indol-6-yl)urea \|...) Show SMILES CONC(=O)Nc1ccc2c(c[nH]c2c1)-c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182878 (3-(pyridin-4-yl)-1H-indole \| CHEMBL380071 \| cid_64...) Show SMILES c1[nH]c2ccccc2c1-c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182918 (1-(benzyloxy)-3-(3-cyano-1-methyl-1H-indol-6-yl)ur...) Show SMILES Cn1cc(C#N)c2ccc(NC(=O)NOCc3ccccc3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182923 (1-(benzyloxy)-3-(3-(pyridin-4-yl)-1H-indol-7-yl)ur...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182916 (1-methyl-6-({[(methylamino)oxy]carbonyl}amino)-1H-...) Show SMILES CNOC(=O)Nc1ccc2c(cn(C)c2c1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182934 (CHEMBL377529 \| N-(3-(pyridin-4-yl)-1H-indol-7-yl)b...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182877 (1-methyl-1H-indole-3-carbonitrile \| CHEMBL205035) Show SMILES Cn1cc(C#N)c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182928 (CHEMBL205236 \| N-(3-cyano-1-methyl-1H-indol-6-yl)b...) Show SMILES Cn1cc(C#N)c2ccc(NS(=O)(=O)c3ccccc3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182930 (3-(3-cyano-1-methyl-1H-indol-7-yl)-1-methyl-1-phen...) Show SMILES CN(C(=O)Nc1cccc2c(cn(C)c12)C#N)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182917 (3-(3-cyano-1H-indol-6-yl)-1-methyl-1-phenylurea \| ...) Show SMILES CN(C(=O)Nc1ccc2c(c[nH]c2c1)C#N)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182932 (3-(3-cyano-1-methyl-1H-indol-6-yl)-1-methyl-1-phen...) Show SMILES CN(C(=O)Nc1ccc2c(cn(C)c2c1)C#N)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182929 (1-methyl-1-phenyl-3-(3-(pyridin-4-yl)-1H-indol-7-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50127708 ((1H)-indole-3-carbonitrile \| 1H-Indole-3-carbonitr...) Show SMILES N#Cc1c[nH]c2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182926 (CHEMBL378273 \| N-(3-cyano-1-methyl-1H-indol-6-yl)(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182933 (7-(benzo[d]oxazol-2-ylamino)-1-methyl-1H-indole-3-...) Show SMILES Cn1cc(C#N)c2cccc(Nc3nc4ccccc4o3)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens (Human))	BDBM50182924 (6-(benzyloxy)-1H-indole-3-carbonitrile \| CHEMBL377...) Show SMILES N#Cc1c[nH]c2cc(OCc3ccccc3)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of IMPDH2				Bioorg Med Chem Lett 16: 2539-42 (2006) Article DOI: 10.1016/j.bmcl.2006.01.090 BindingDB Entry DOI: 10.7270/Q2F76C4P
UCB Celltech Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%