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PubMed code 16509587

Compile data set for download or QSAR
Found 72 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50117108
PNG
(4-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[nH+]cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)/p+1
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PubMed
 0.0140n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50117109
PNG
(1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccncc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)
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PubMed
 0.0460n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 0.350n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 0.440n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 0.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 0.550n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183526
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccccn1C)n1nc(nc21)-c1ccco1 |w:11.11|
Show InChI InChI=1S/C18H15N9O2/c1-25-8-4-3-7-13(25)19-18(28)22-17-21-14-11(10-26(2)23-14)16-20-15(24-27(16)17)12-6-5-9-29-12/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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 1.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183522
PNG
(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1sccc1NC(=O)Nc1nc2nn(C)cc2c2nc(nn12)-c1ccco1
Show InChI InChI=1S/C17H14N8O2S/c1-9-11(5-7-28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)12-4-3-6-27-12/h3-8H,1-2H3,(H2,18,20,21,22,26)
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 3.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183530
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccc[n+]1[O-])n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-10-13(22-24)20-16(21-17(27)18-12-6-2-3-7-25(12)28)26-15(10)19-14(23-26)11-5-4-8-29-11/h2-9H,1H3,(H2,18,20,21,22,27)
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 3.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183520
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+](C)c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C18H15N9O2/c1-25-7-3-5-11(9-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-6-4-8-29-13/h3-10H,1-2H3,(H-,19,21,22,23,28)/p+1
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 5.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183527
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+]([O-])c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-2-6-25(28)8-10)26-15(11)19-14(23-26)12-5-3-7-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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 10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183528
PNG
(5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(nn23)-c2ccco2)s1
Show InChI InChI=1S/C17H14N8O2S/c1-9-5-6-12(28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)11-4-3-7-27-11/h3-8H,1-2H3,(H2,18,20,21,22,26)
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 10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183516
PNG
(5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccoc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-7-10-12(21-23)19-15(20-16(25)17-9-4-6-26-8-9)24-14(10)18-13(22-24)11-3-2-5-27-11/h2-8H,1H3,(H2,17,19,20,21,25)
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 11n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183529
PNG
(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc3ccccc3o1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C20H14N8O3/c1-27-10-12-16(25-27)23-19(28-18(12)22-17(26-28)14-7-4-8-30-14)24-20(29)21-15-9-11-5-2-3-6-13(11)31-15/h2-10H,1H3,(H2,21,23,24,25,29)
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 12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183524
PNG
(5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccco1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-8-9-12(21-23)19-15(20-16(25)17-11-5-3-7-27-11)24-14(9)18-13(22-24)10-4-2-6-26-10/h2-8H,1H3,(H2,17,19,20,21,25)
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 16n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183523
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[n+]([O-])cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-6-25(28)7-5-10)26-15(11)19-14(23-26)12-3-2-8-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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 21n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183521
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccn(C)cc1)n1nc(nc21)-c1ccco1 |(-10.58,-30.28,;-9.82,-28.94,;-8.3,-28.76,;-7.99,-27.26,;-9.33,-26.5,;-10.46,-27.54,;-9.32,-24.95,;-7.99,-24.17,;-7.99,-22.62,;-6.66,-21.85,;-6.66,-20.31,;-5.32,-22.62,;-3.98,-21.85,;-3.98,-20.32,;-2.65,-19.55,;-1.31,-20.32,;.02,-19.54,;-1.3,-21.86,;-2.64,-22.63,;-6.66,-24.95,;-5.19,-24.47,;-4.29,-25.71,;-5.19,-26.96,;-6.66,-26.49,;-2.74,-25.71,;-1.84,-24.46,;-.38,-24.91,;-.37,-26.48,;-1.83,-26.96,)|
Show InChI InChI=1S/C18H15N9O2/c1-25-7-5-11(6-8-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-4-3-9-29-13/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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 28n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183520
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+](C)c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C18H15N9O2/c1-25-7-3-5-11(9-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-6-4-8-29-13/h3-10H,1-2H3,(H-,19,21,22,23,28)/p+1
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 42n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183529
PNG
(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc3ccccc3o1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C20H14N8O3/c1-27-10-12-16(25-27)23-19(28-18(12)22-17(26-28)14-7-4-8-30-14)24-20(29)21-15-9-11-5-2-3-6-13(11)31-15/h2-10H,1H3,(H2,21,23,24,25,29)
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 60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183526
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccccn1C)n1nc(nc21)-c1ccco1 |w:11.11|
Show InChI InChI=1S/C18H15N9O2/c1-25-8-4-3-7-13(25)19-18(28)22-17-21-14-11(10-26(2)23-14)16-20-15(24-27(16)17)12-6-5-9-29-12/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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 64n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50117109
PNG
(1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccncc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 65n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183527
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+]([O-])c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-2-6-25(28)8-10)26-15(11)19-14(23-26)12-5-3-7-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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 75n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50117108
PNG
(4-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[nH+]cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)/p+1
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 110n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183530
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccc[n+]1[O-])n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-10-13(22-24)20-16(21-17(27)18-12-6-2-3-7-25(12)28)26-15(10)19-14(23-26)11-5-4-8-29-11/h2-9H,1H3,(H2,18,20,21,22,27)
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 110n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50183519
PNG
(5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc3ccccc3n1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C21H15N9O2/c1-29-11-13-17(27-29)25-20(30-19(13)24-18(28-30)15-7-4-10-32-15)26-21(31)23-16-9-8-12-5-2-3-6-14(12)22-16/h2-11H,1H3,(H2,22,23,25,26,27,31)
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 110n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 125n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 140n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183523
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[n+]([O-])cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-6-25(28)7-5-10)26-15(11)19-14(23-26)12-3-2-8-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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 153n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 155n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 180n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 210n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 230n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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 245n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50117109
PNG
(1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccncc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 260n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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 265n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183521
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccn(C)cc1)n1nc(nc21)-c1ccco1 |(-10.58,-30.28,;-9.82,-28.94,;-8.3,-28.76,;-7.99,-27.26,;-9.33,-26.5,;-10.46,-27.54,;-9.32,-24.95,;-7.99,-24.17,;-7.99,-22.62,;-6.66,-21.85,;-6.66,-20.31,;-5.32,-22.62,;-3.98,-21.85,;-3.98,-20.32,;-2.65,-19.55,;-1.31,-20.32,;.02,-19.54,;-1.3,-21.86,;-2.64,-22.63,;-6.66,-24.95,;-5.19,-24.47,;-4.29,-25.71,;-5.19,-26.96,;-6.66,-26.49,;-2.74,-25.71,;-1.84,-24.46,;-.38,-24.91,;-.37,-26.48,;-1.83,-26.96,)|
Show InChI InChI=1S/C18H15N9O2/c1-25-7-5-11(6-8-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-4-3-9-29-13/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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 282n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183520
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+](C)c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C18H15N9O2/c1-25-7-3-5-11(9-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-6-4-8-29-13/h3-10H,1-2H3,(H-,19,21,22,23,28)/p+1
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 330n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183524
PNG
(5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccco1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-8-9-12(21-23)19-15(20-16(25)17-11-5-3-7-27-11)24-14(9)18-13(22-24)10-4-2-6-26-10/h2-8H,1H3,(H2,17,19,20,21,25)
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 350n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50117108
PNG
(4-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[nH+]cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)/p+1
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 355n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183516
PNG
(5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccoc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-7-10-12(21-23)19-15(20-16(25)17-9-4-6-26-8-9)24-14(10)18-13(22-24)11-3-2-5-27-11/h2-8H,1H3,(H2,17,19,20,21,25)
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 400n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183526
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccccn1C)n1nc(nc21)-c1ccco1 |w:11.11|
Show InChI InChI=1S/C18H15N9O2/c1-25-8-4-3-7-13(25)19-18(28)22-17-21-14-11(10-26(2)23-14)16-20-15(24-27(16)17)12-6-5-9-29-12/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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 400n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183522
PNG
(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1sccc1NC(=O)Nc1nc2nn(C)cc2c2nc(nn12)-c1ccco1
Show InChI InChI=1S/C17H14N8O2S/c1-9-11(5-7-28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)12-4-3-6-27-12/h3-8H,1-2H3,(H2,18,20,21,22,26)
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 410n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183527
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+]([O-])c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-2-6-25(28)8-10)26-15(11)19-14(23-26)12-5-3-7-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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 550n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183530
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccc[n+]1[O-])n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-10-13(22-24)20-16(21-17(27)18-12-6-2-3-7-25(12)28)26-15(10)19-14(23-26)11-5-4-8-29-11/h2-9H,1H3,(H2,18,20,21,22,27)
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 800n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183519
PNG
(5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc3ccccc3n1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C21H15N9O2/c1-29-11-13-17(27-29)25-20(30-19(13)24-18(28-30)15-7-4-10-32-15)26-21(31)23-16-9-8-12-5-2-3-6-14(12)22-16/h2-11H,1H3,(H2,22,23,25,26,27,31)
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 810n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM50183528
PNG
(5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(nn23)-c2ccco2)s1
Show InChI InChI=1S/C17H14N8O2S/c1-9-5-6-12(28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)11-4-3-7-27-11/h3-8H,1-2H3,(H2,18,20,21,22,26)
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 920n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183523
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[n+]([O-])cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-6-25(28)7-5-10)26-15(11)19-14(23-26)12-3-2-8-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183524
PNG
(5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccco1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-8-9-12(21-23)19-15(20-16(25)17-11-5-3-7-27-11)24-14(9)18-13(22-24)10-4-2-6-26-10/h2-8H,1H3,(H2,17,19,20,21,25)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183519
PNG
(5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc3ccccc3n1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C21H15N9O2/c1-29-11-13-17(27-29)25-20(30-19(13)24-18(28-30)15-7-4-10-32-15)26-21(31)23-16-9-8-12-5-2-3-6-14(12)22-16/h2-11H,1H3,(H2,22,23,25,26,27,31)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183528
PNG
(5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(nn23)-c2ccco2)s1
Show InChI InChI=1S/C17H14N8O2S/c1-9-5-6-12(28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)11-4-3-7-27-11/h3-8H,1-2H3,(H2,18,20,21,22,26)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183516
PNG
(5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccoc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-7-10-12(21-23)19-15(20-16(25)17-9-4-6-26-8-9)24-14(10)18-13(22-24)11-3-2-5-27-11/h2-8H,1H3,(H2,17,19,20,21,25)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183529
PNG
(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc3ccccc3o1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C20H14N8O3/c1-27-10-12-16(25-27)23-19(28-18(12)22-17(26-28)14-7-4-8-30-14)24-20(29)21-15-9-11-5-2-3-6-13(11)31-15/h2-10H,1H3,(H2,21,23,24,25,29)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183521
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccn(C)cc1)n1nc(nc21)-c1ccco1 |(-10.58,-30.28,;-9.82,-28.94,;-8.3,-28.76,;-7.99,-27.26,;-9.33,-26.5,;-10.46,-27.54,;-9.32,-24.95,;-7.99,-24.17,;-7.99,-22.62,;-6.66,-21.85,;-6.66,-20.31,;-5.32,-22.62,;-3.98,-21.85,;-3.98,-20.32,;-2.65,-19.55,;-1.31,-20.32,;.02,-19.54,;-1.3,-21.86,;-2.64,-22.63,;-6.66,-24.95,;-5.19,-24.47,;-4.29,-25.71,;-5.19,-26.96,;-6.66,-26.49,;-2.74,-25.71,;-1.84,-24.46,;-.38,-24.91,;-.37,-26.48,;-1.83,-26.96,)|
Show InChI InChI=1S/C18H15N9O2/c1-25-7-5-11(6-8-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-4-3-9-29-13/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Homo sapiens (Human))		BDBM50183522
PNG
(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1sccc1NC(=O)Nc1nc2nn(C)cc2c2nc(nn12)-c1ccco1
Show InChI InChI=1S/C17H14N8O2S/c1-9-11(5-7-28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)12-4-3-6-27-12/h3-8H,1-2H3,(H2,18,20,21,22,26)
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>1.00E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183520
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+](C)c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C18H15N9O2/c1-25-7-3-5-11(9-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-6-4-8-29-13/h3-10H,1-2H3,(H-,19,21,22,23,28)/p+1
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n/an/a 244n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183529
PNG
(5-[[(benzofuran-2-yl)amino]carbonyl]amino-8-methyl...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc3ccccc3o1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C20H14N8O3/c1-27-10-12-16(25-27)23-19(28-18(12)22-17(26-28)14-7-4-8-30-14)24-20(29)21-15-9-11-5-2-3-6-13(11)31-15/h2-10H,1H3,(H2,21,23,24,25,29)
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n/an/a 250n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183527
PNG
(3-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc[n+]([O-])c1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-2-6-25(28)8-10)26-15(11)19-14(23-26)12-5-3-7-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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n/an/a 260n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183526
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccccn1C)n1nc(nc21)-c1ccco1 |w:11.11|
Show InChI InChI=1S/C18H15N9O2/c1-25-8-4-3-7-13(25)19-18(28)22-17-21-14-11(10-26(2)23-14)16-20-15(24-27(16)17)12-6-5-9-29-12/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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n/an/a 280n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183530
PNG
(2-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccc[n+]1[O-])n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-10-13(22-24)20-16(21-17(27)18-12-6-2-3-7-25(12)28)26-15(10)19-14(23-26)11-5-4-8-29-11/h2-9H,1H3,(H2,18,20,21,22,27)
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n/an/a 320n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183522
PNG
(5-[[(2-methyl-thiophen-3-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1sccc1NC(=O)Nc1nc2nn(C)cc2c2nc(nn12)-c1ccco1
Show InChI InChI=1S/C17H14N8O2S/c1-9-11(5-7-28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)12-4-3-6-27-12/h3-8H,1-2H3,(H2,18,20,21,22,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183525
PNG
(5-[[(3-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cccnc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-2-6-18-8-10)26-15(11)20-14(24-26)12-5-3-7-28-12/h2-9H,1H3,(H2,19,21,22,23,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183521
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)[NH+]=c1ccn(C)cc1)n1nc(nc21)-c1ccco1 |(-10.58,-30.28,;-9.82,-28.94,;-8.3,-28.76,;-7.99,-27.26,;-9.33,-26.5,;-10.46,-27.54,;-9.32,-24.95,;-7.99,-24.17,;-7.99,-22.62,;-6.66,-21.85,;-6.66,-20.31,;-5.32,-22.62,;-3.98,-21.85,;-3.98,-20.32,;-2.65,-19.55,;-1.31,-20.32,;.02,-19.54,;-1.3,-21.86,;-2.64,-22.63,;-6.66,-24.95,;-5.19,-24.47,;-4.29,-25.71,;-5.19,-26.96,;-6.66,-26.49,;-2.74,-25.71,;-1.84,-24.46,;-.38,-24.91,;-.37,-26.48,;-1.83,-26.96,)|
Show InChI InChI=1S/C18H15N9O2/c1-25-7-5-11(6-8-25)19-18(28)22-17-21-14-12(10-26(2)23-14)16-20-15(24-27(16)17)13-4-3-9-29-13/h3-10H,1-2H3,(H,21,22,23,28)/p+1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183523
PNG
(4-[3-(2-furan-2-yl-8-methy-8H-pyrazolo[4,3-e][1,2,...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[n+]([O-])cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O3/c1-24-9-11-13(22-24)20-16(21-17(27)18-10-4-6-25(28)7-5-10)26-15(11)19-14(23-26)12-3-2-8-29-12/h2-9H,1H3,(H2,18,20,21,22,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50117108
PNG
(4-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1cc[nH+]cc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)/p+1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183528
PNG
(5-[[(5-methyl-thiophen-2-yl)amino]carbonyl]amino-8...)
Show SMILES Cc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(nn23)-c2ccco2)s1
Show InChI InChI=1S/C17H14N8O2S/c1-9-5-6-12(28-9)18-17(26)21-16-20-13-10(8-24(2)22-13)15-19-14(23-25(15)16)11-4-3-7-27-11/h3-8H,1-2H3,(H2,18,20,21,22,26)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183524
PNG
(5-[[(2-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccco1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-8-9-12(21-23)19-15(20-16(25)17-11-5-3-7-27-11)24-14(9)18-13(22-24)10-4-2-6-26-10/h2-8H,1H3,(H2,17,19,20,21,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183516
PNG
(5-[[(3-furyl)amino]carbonyl]amino-8-methyl-2-(2-fu...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccoc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C16H12N8O3/c1-23-7-10-12(21-23)19-15(20-16(25)17-9-4-6-26-8-9)24-14(10)18-13(22-24)11-3-2-5-27-11/h2-8H,1H3,(H2,17,19,20,21,25)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50117109
PNG
(1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccncc1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-11-13(23-25)21-16(22-17(27)19-10-4-6-18-7-5-10)26-15(11)20-14(24-26)12-3-2-8-28-12/h2-9H,1H3,(H2,18,19,21,22,23,27)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183515
PNG
(5-[[(2-pyridyl)amino]carbonyl]amino-8-methyl-2-(2-...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccccn1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C17H13N9O2/c1-25-9-10-13(23-25)21-16(22-17(27)19-12-6-2-3-7-18-12)26-15(10)20-14(24-26)11-5-4-8-28-11/h2-9H,1H3,(H2,18,19,21,22,23,27)
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Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50183519
PNG
(5-[[(quinolin-2-yl)amino]carbonyl]amino-8-methyl-2...)
Show SMILES Cn1cc2c(n1)nc(NC(=O)Nc1ccc3ccccc3n1)n1nc(nc21)-c1ccco1
Show InChI InChI=1S/C21H15N9O2/c1-29-11-13-17(27-29)25-20(30-19(13)24-18(28-30)15-7-4-10-32-15)26-21(31)23-16-9-8-12-5-2-3-6-14(12)22-16/h2-11H,1H3,(H2,22,23,25,26,27,31)
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Universit£ degli Studi di Trieste

Curated by ChEMBL


Assay Description
Inhibition of NECA-stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptor

J Med Chem 49: 1720-9 (2006)


Article DOI: 10.1021/jm051147+
BindingDB Entry DOI: 10.7270/Q26974CT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%