Affinity Data by PubMed id=16570912

PubMed code 16570912

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184850 (CHEMBL534938 \| N'-[2-(4-fluorophenyl)allyl]-N-meth...) Show SMILES CNNCC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184849 (CHEMBL536057 \| N'-(2-phenylallyl)hydrazine hydroch...) Show SMILES NNCC(=C)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184847 (CHEMBL538327 \| N'-[2-(4-fluorophenyl)allyl]-N-ethy...) Show SMILES CCNNCC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184853 (CHEMBL536060 \| N'-[2-(4-chlorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(Cl)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184848 (CHEMBL553631 \| N'-[2-(2-methylphenyl)allyl]hydrazi...) Show SMILES Cc1ccccc1C(=C)CNN Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184843 (CHEMBL556769 \| N'-[(E)-(2-phenyl-3-fluoroallyl)]hy...) Show SMILES NNC\C(=C\F)c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184844 (CHEMBL536059 \| N'-[2-(4-fluorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184846 (CHEMBL540369 \| N'-[2-(4-fluorophenyl)allyl]-N'-met...) Show SMILES CN(N)CC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184845 (CHEMBL559381 \| N'-[2-(4-fluorophenyl)allyl]-N'-iso...) Show SMILES CC(C)N(N)CC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184851 (CHEMBL557373 \| N'-[2-(4-fluorophenyl)allyl]-N'-eth...) Show SMILES CCN(N)CC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50184843 (CHEMBL556769 \| N'-[(E)-(2-phenyl-3-fluoroallyl)]hy...) Show SMILES NNC\C(=C\F)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184842 (CHEMBL534491 \| N'-[2-(4-fluorophenyl)allyl]-N-isop...) Show SMILES CC(C)NNCC(=C)c1ccc(F)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184855 (CHEMBL536740 \| N'-[2-(4-fluorophenyl)allyl]-N-benz...) Show SMILES Fc1ccc(cc1)C(=C)CNNCc1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184852 (CHEMBL536509 \| N'-[2-(4-fluorophenyl)allyl]-N'-ben...) Show SMILES NN(CC(=C)c1ccc(F)cc1)Cc1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50184853 (CHEMBL536060 \| N'-[2-(4-chlorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50184849 (CHEMBL536057 \| N'-(2-phenylallyl)hydrazine hydroch...) Show SMILES NNCC(=C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50184848 (CHEMBL553631 \| N'-[2-(2-methylphenyl)allyl]hydrazi...) Show SMILES Cc1ccccc1C(=C)CNN Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50184854 (CHEMBL536510 \| N'-[2-(4-chlorophenyl)allyl]-N,N'-d...) Show SMILES CNN(C)CC(=C)c1ccc(Cl)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of SSAO in rat lung				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50184843 (CHEMBL556769 \| N'-[(E)-(2-phenyl-3-fluoroallyl)]hy...) Show SMILES NNC\C(=C\F)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50184844 (CHEMBL536059 \| N'-[2-(4-fluorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-A				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50184853 (CHEMBL536060 \| N'-[2-(4-chlorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50184849 (CHEMBL536057 \| N'-(2-phenylallyl)hydrazine hydroch...) Show SMILES NNCC(=C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50184844 (CHEMBL536059 \| N'-[2-(4-fluorophenyl)allyl]hydrazi...) Show SMILES NNCC(=C)c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50184848 (CHEMBL553631 \| N'-[2-(2-methylphenyl)allyl]hydrazi...) Show SMILES Cc1ccccc1C(=C)CNN Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Jolla Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of recombinant human MAO-B				J Med Chem 49: 2166-73 (2006) Article DOI: 10.1021/jm050538l BindingDB Entry DOI: 10.7270/Q2JM2BFH
La Jolla Pharmaceutical Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%